Using ultrasound to evaluate lung diseases
Official title: Synergistic Assessment of Ultrasound Data and Respiratory physiOlogical Signals in luNg Diseases
Run by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT06068647 · Data updated 2026-11-12
This study is testing whether lung ultrasound can help doctors better understand and monitor lung diseases like interstitial lung disease and COPD in both hospital patients and those visiting outpatient clinics.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 25 (estimated) |
| Sponsor | Fondazione Policlinico Universitario Agostino Gemelli IRCCS Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Rome) |
| Status | Recruiting |
| Started | March 22, 2023 |
| Main results expected | June 30, 2026 |
| Study ends | September 30, 2026 |
| Registry record updated | May 20, 2026 |
| Trial ID | NCT06068647 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include inpatients with exacerbated interstitial lung diseases or infectious interstitial pneumonia, as well as outpatients with stable COPD or emphysema.
✕Probably not a fit
Patients with severe skin conditions or those who have a history of allergic reactions to adhesives may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study explores the use of lung ultrasound to assess various lung conditions, including interstitial lung disease and chronic obstructive pulmonary disease (COPD). It aims to investigate the physical mechanisms behind ultrasound artifacts that can provide diagnostic information about the lung's state when it is still aerated. The study will involve both inpatients and outpatients, utilizing lung ultrasound alongside computed tomography scans and cardio-respiratory evaluations to gather comprehensive data. The goal is to enhance understanding of lung ultrasound's capabilities in detecting and monitoring lung pathologies.
Why it matters
Potential benefit: If successful, this study could improve diagnostic accuracy and monitoring of lung diseases, leading to better patient outcomes.
How similar studies have gone: While lung ultrasound has been widely accepted for certain applications, the specific exploration of non-consolidated lung tissue using ultrasound artifacts is a relatively novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * inpatients admitted to the hospital due to diffuse interstitial lung diseases during exacerbation OR infectious interstitial pneumonia not caused by SARS-CoV-2 OR acute exacerbation of chronic obstructive pulmonary disease. * Outpatients with pulmonary paraseptal and/or panlobular emphysema and/or chronic obstructive pulmonary disease during stable phase. * Patients able to give written informed consent. Exclusion Criteria: * history of skin irritation, redness, itching or allergic cutaneous symptoms. * Allergic reactions to adhesives or hydrogels. * Family history of adhesive skin allergies. * Presence of severe skin conditions such as wounds, burns or on any damaged skin. * Presence of strong magnetic fields in the study setting. * Presence of electromagnetic disturbances or significant ionizing radiation sources which might lead to signal artifacts. * Use of external cardiac defibrillators. * Use of diaphragmatic pacers. * Use of extra cardiac stimulators. * Pregnancy. * Pediatric population.
Where it's running
-
Fondazione Policlinico Universitario A. Gemelli IRCCS
Rome, Italy Recruiting
Study contacts
- Principal investigator: Riccardo Inchingolo, MD, PhD — Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Study coordinator: Riccardo Inchingolo, MD, PhD
- Email: riccardo.inchingolo@policlinicogemelli.it
- Phone: +390630156062
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.