Clinical trial Recruiting at 1 site Observational Ages 18 and up

Effect of endobronchial valves on diaphragm movement in COPD patients

Official title: The Effect of Treatment of Emphysema With Endobronchial Valves on the Diaphragm Mobility

Run by Aarhus University Hospital · NCT06163131 · Data updated 2026-11-12

This study tests if putting in endobronchial valves can help improve diaphragm movement in people with COPD and see if that leads to better breathing and overall health.

More Chronic Obstructive Pulmonary Disease trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment35 (estimated)
SponsorAarhus University Hospital
Academic / other
Locations1 site (Aarhus)
StatusRecruiting
StartedNovember 27, 2023
Main results expectedNovember 27, 2026
Study endsApril 1, 2027
Registry record updatedDecember 8, 2023
Trial IDNCT06163131 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients with severe emphysema who are selected for treatment with endobronchial valves.

Probably not a fit

Patients with neuromuscular diseases affecting diaphragm function or those with pleural effusion at the time of evaluation may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates how the insertion of endobronchial valves affects diaphragm mobility in patients with chronic obstructive pulmonary disease (COPD) and emphysema. The study aims to determine if diaphragm movement improves post-treatment and whether this improvement correlates with enhanced symptoms, lung function, and physical ability. Additionally, it will explore if immediate ultrasound evaluations can predict clinical outcomes related to diaphragm function and atelectasis development.

Why it matters

Potential benefit: If successful, this treatment could significantly improve breathing and quality of life for patients with severe emphysema.

How similar studies have gone: While the use of endobronchial valves has been explored in other studies, the specific focus on diaphragm mobility in this context is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients selected to receive treatment with endobronchial valves
2. Signed informed consent

Exclusion Criteria:

1. Neuromuscular disease interfering with diaphragm function
2. Pleural effusion at time of preoperative or 90-days postoperative ultrasound

Where it's running

  • Aarhus University Hospital
    Aarhus, Denmark
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.