Effect of endobronchial valves on diaphragm movement in COPD patients
Official title: The Effect of Treatment of Emphysema With Endobronchial Valves on the Diaphragm Mobility
Run by Aarhus University Hospital · NCT06163131 · Data updated 2026-11-12
This study tests if putting in endobronchial valves can help improve diaphragm movement in people with COPD and see if that leads to better breathing and overall health.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 35 (estimated) |
| Sponsor | Aarhus University Hospital Academic / other |
| Locations | 1 site (Aarhus) |
| Status | Recruiting |
| Started | November 27, 2023 |
| Main results expected | November 27, 2026 |
| Study ends | April 1, 2027 |
| Registry record updated | December 8, 2023 |
| Trial ID | NCT06163131 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients with severe emphysema who are selected for treatment with endobronchial valves.
✕Probably not a fit
Patients with neuromuscular diseases affecting diaphragm function or those with pleural effusion at the time of evaluation may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates how the insertion of endobronchial valves affects diaphragm mobility in patients with chronic obstructive pulmonary disease (COPD) and emphysema. The study aims to determine if diaphragm movement improves post-treatment and whether this improvement correlates with enhanced symptoms, lung function, and physical ability. Additionally, it will explore if immediate ultrasound evaluations can predict clinical outcomes related to diaphragm function and atelectasis development.
Why it matters
Potential benefit: If successful, this treatment could significantly improve breathing and quality of life for patients with severe emphysema.
How similar studies have gone: While the use of endobronchial valves has been explored in other studies, the specific focus on diaphragm mobility in this context is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients selected to receive treatment with endobronchial valves 2. Signed informed consent Exclusion Criteria: 1. Neuromuscular disease interfering with diaphragm function 2. Pleural effusion at time of preoperative or 90-days postoperative ultrasound
Where it's running
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Aarhus University Hospital
Aarhus, Denmark Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.