Effect of endobronchial valves on diaphragm movement in COPD patients
The Effect of Treatment of Emphysema With Endobronchial Valves on the Diaphragm Mobility
This study tests if putting in endobronchial valves can help improve diaphragm movement in people with COPD and see if that leads to better breathing and overall health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 35 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Aarhus University Hospital Academic / other |
| Locations | 1 site (Aarhus) |
| Trial ID | NCT06163131 on ClinicalTrials.gov |
What this trial studies
This observational study investigates how the insertion of endobronchial valves affects diaphragm mobility in patients with chronic obstructive pulmonary disease (COPD) and emphysema. The study aims to determine if diaphragm movement improves post-treatment and whether this improvement correlates with enhanced symptoms, lung function, and physical ability. Additionally, it will explore if immediate ultrasound evaluations can predict clinical outcomes related to diaphragm function and atelectasis development.
Who should consider this trial
Good fit: Ideal candidates are patients with severe emphysema who are selected for treatment with endobronchial valves.
Not a fit: Patients with neuromuscular diseases affecting diaphragm function or those with pleural effusion at the time of evaluation may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly improve breathing and quality of life for patients with severe emphysema.
How similar studies have performed: While the use of endobronchial valves has been explored in other studies, the specific focus on diaphragm mobility in this context is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients selected to receive treatment with endobronchial valves 2. Signed informed consent Exclusion Criteria: 1. Neuromuscular disease interfering with diaphragm function 2. Pleural effusion at time of preoperative or 90-days postoperative ultrasound
Where this trial is running
Aarhus
- Aarhus University Hospital — Aarhus, Denmark (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.