Using technology to treat sleep apnea in people with prediabetes
Technology-Supported Treatment of Sleep Apnea in Prediabetes
This study is testing if adding a CPAP machine to a weight loss program can help people with prediabetes and sleep apnea improve their health.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 174 (estimated) |
| Ages | 20 Years to 65 Years |
| Sex | All |
| Sponsor | University of Chicago Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Trial ID | NCT04225507 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of adding continuous positive airway pressure (CPAP) treatment to a lifestyle intervention aimed at weight loss in individuals with prediabetes and sleep apnea. Participants will be randomly assigned to either a lifestyle intervention group or a lifestyle plus CPAP group for a duration of six months. Both groups will receive metabolic and cardiovascular assessments at the beginning and end of the study, while also utilizing a smartphone app for tracking progress and receiving weekly coaching calls to enhance adherence to the interventions.
Who should consider this trial
Good fit: Ideal candidates for this study are overweight or obese individuals diagnosed with prediabetes and sleep apnea.
Not a fit: Patients who are already diabetic or enrolled in a formal weight loss program may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve cardiometabolic outcomes in individuals with prediabetes and sleep apnea, potentially preventing the progression to diabetes.
How similar studies have performed: While the combination of CPAP and lifestyle interventions is a novel approach in this specific population, similar studies have shown promising results in other contexts.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Overweight or obese * Prediabetes * Sleep apnea Exclusion Criteria: * Diabetic * enrolled in a formal weight loss program * Any underlying disease likely to limit life span and/or increase risk of interventions
Where this trial is running
Chicago, Illinois
- University of Chicago — Chicago, Illinois, United States (Recruiting)
Study contacts
- Principal investigator: Esra Tasali, MD — University of Chicago
- Study coordinator: Esra Tasali, MD
- Email: etasali@bsd.uchicago.edu
- Phone: 7738342663
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.