Home › Trials › NCT05247177
Clinical trial No longer in our active list Interventional Ages 60 to 90

Using multimodal anesthesia for elderly patients undergoing lumbar spine surgery

Official title: Effects of Multimodal General Anesthesia for Older Patients Undergoing Lumbar Spine Fusion Surgery: a Randomized Controlled Trial

Run by National Taiwan University Hospital · NCT05247177 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing a new way of using anesthesia during back surgery to see if it helps older patients recover better and have fewer complications like confusion after the surgery.

Quick facts

Study typeInterventional
Ages60 Years to 90 Years
SexAll
Enrollment160 (estimated)
SponsorNational Taiwan University Hospital
Academic / other
Locations1 site (Taipei)
Trial IDNCT05247177 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are elderly patients aged 60 and above who are scheduled for elective lumbar spine surgery.

Probably not a fit

Patients with a history of dementia, impaired liver or renal function, or significant cardiac dysfunction may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effects of multimodal general anesthesia on the recovery of elderly patients undergoing lumbar spine fusion surgery. It utilizes a combination of sevoflurane, ketamine, and dexmedetomidine, guided by electroencephalography density spectrum array, to enhance anesthetic effects while minimizing dosages. The goal is to improve postoperative recovery and reduce complications such as delirium and cognitive impairment, which are common in this patient population. By comparing this approach to conventional anesthesia, the study aims to identify potential benefits in recovery profiles.

Why it matters

Potential benefit: If successful, this approach could significantly enhance recovery outcomes and reduce postoperative complications for elderly patients undergoing lumbar spine surgery.

How similar studies have gone: Other studies have shown promising results with multimodal anesthesia approaches, suggesting potential for success in this novel application.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion criteria:

1. patients with ages at least 60-year undergoing elective lumbar spine surgery

Exclusion:

1. A history of dementia
2. Impaired liver function, eg. AST or ALT \>100; liver cirrhosis \> Child B class
3. Impaired renal function, cGFR\< 60 ml/min/1.73 m2
4. Cardiac dysfunction, such as heart failure \> NYHA class II

Where it's running

  • National Taiwan University Hospital
    Taipei, Taiwan     Recruiting

Study contacts

  • Principal investigator: Chun-Yu Wu, MD — National Taiwan University Hospital
  • Study coordinator: Chun-Yu Wu
  • Email: longersolo@gmail.com
  • Phone: 0972653376

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov ↗ Find more trials like this →
Browse more
National Taiwan University Hospital 278
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.