rTMS-primed self-controlled practice for people with Parkinson’s disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study explores whether combining repetitive transcranial magnetic stimulation (rTMS) with self-controlled motor training enhances rehabilitation outcomes in Parkinson’s disease. Participants will receive rTMS priming before or during physical therapy that allows self-selected training parameters, aiming to improve motor learning and engagement. The trial investigates whether targeting different cortical areas yields different benefits and whether the approach is feasible in an outpatient setting. Eligible adults with Parkinson’s disease must be able to stand/walk for 10 minutes and have adequate cognitive function. Safety considerations include exclusion of individuals with contraindications to TMS or other neurological/medical conditions that could confound results.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* diagnosed of PD by neurologists and age above 18 years old
* able to follow the researcher's instruction (the Montreal Cognitive Assessment ≥ 24)
* able to stand and walk independently for 10 minutes with or without assistive devices

Exclusion Criteria:

* have neurological disorders other than PD (e.g., Parkinson plus syndrome, cognitive impairment, dementia, stroke)
* have contraindications to receive TMS, such as a pacemaker or deep brain stimulator implanted in the body
* a self-history of seizure or a family history of epilepsy
* pregnancy
* unstable medical conditions that is not under control

Where it's running

• School and Graduate Institute of Physical Therapy
  Taipei, Zhongzheng Dist., Taiwan Recruiting

Study contacts

• Principal investigator: Graduate Institute of Physical Therapy — National Taiwan University
• Study coordinator: Ya-Yun Lee, PhD
• Email: yayunlee@ntu.edu.tw
• Phone: +886-2-33668155

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.