Using MRI to predict outcomes in stroke patients treated with thrombectomy
Official title: Predictive Multimodal MRI Factors in Subacute Cerebral Artery Occlusiontreated by Thrombectomy (PIMISUTT
Run by Poitiers University Hospital · NCT04651010 · Data updated 2026-11-12
This study is testing if special MRI scans can help predict how well stroke patients will recover after they receive a thrombectomy treatment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Poitiers University Hospital Academic / other |
| Locations | 1 site (Poitiers) |
| Status | Recruiting |
| Started | November 15, 2021 |
| Main results expected | August 15, 2028 |
| Study ends | August 15, 2028 |
| Registry record updated | October 13, 2026 |
| Trial ID | NCT04651010 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older with acute middle cerebral artery occlusion who are undergoing thrombectomy.
✕Probably not a fit
Patients with cognitive impairments or those unable to undergo MRI due to contraindications may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the use of multimodal MRI to assess metabolic and functional parameters in patients with acute middle cerebral artery occlusion who are treated with thrombectomy. By measuring these parameters between 12 and 24 hours post-stroke, the study aims to identify early radiologic predictors of clinical outcomes, evaluated using the modified Rankin score at three months. The goal is to enhance understanding of factors influencing recovery in this patient population.
Why it matters
Potential benefit: If successful, this study could lead to improved prediction of clinical outcomes for stroke patients, allowing for better individualized treatment plans.
How similar studies have gone: While there have been studies exploring MRI in stroke assessment, this specific approach focusing on early predictive factors in thrombectomy patients is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged ≥ 18 years old * Hospitalized at the Poitiers University Hospital * Acute middle cerebral artery occlusion diagnosed by CT-scan or MRI * NIHSS score ≥ 6 at admission * To be treated by thrombectomy with or without fibrinolysis * Written information delivered to the patient or his relatives concerning the study and its benefit and risk Exclusion Criteria: * Patients or relatives whom a loyal information about the study cannot be given * Patient with cognitive impairments before MRI. * Patients who cannot undergo MRI because of contraindications * Patients too deteriorated to tolerate one hour long exam
Where it's running
-
CHU Poitiers
Poitiers, France Recruiting
Study contacts
- Study coordinator: Guillaume HERPE, Dr
- Email: guillaume.herpe@chu-poitiers.fr
- Phone: 05 49 44 33 89
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.