Using magnetic stimulation to treat essential tremor
the Effects of Repetitive Transcranial Magnetic Stimulation and Mechanisms in Clinical Function of Essential Tremor
This study is testing if a type of magnetic stimulation can help people with essential tremor feel better by comparing it to a fake treatment.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Second Affiliated Hospital of Soochow University Academic / other |
| Locations | 1 site (Suzhou) |
| Trial ID | NCT06145932 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of repetitive transcranial magnetic stimulation (rTMS) in treating essential tremor through a randomized controlled design. It aims to assess both the clinical outcomes and the underlying electrophysiological mechanisms by measuring changes in clinical scales and TMS-electroencephalogram (TMS-EEG). Participants will receive either real rTMS or a sham treatment to determine the therapy's efficacy. The study seeks to identify a viable treatment option for individuals suffering from essential tremor.
Who should consider this trial
Good fit: Ideal candidates are individuals diagnosed with essential tremor who meet the diagnostic criteria set by the International Parkinson's and Movement Disorders Society.
Not a fit: Patients with brain organic diseases, epilepsy, or other mental health issues, as well as those with contraindications to TMS, will not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could provide a non-invasive option for managing essential tremor symptoms.
How similar studies have performed: Other studies have shown promise with rTMS for various neurological conditions, suggesting potential for success in this novel application for essential tremor.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Diagnosed as essential tremor conforming to the diagnostic criteria for essential tremor in the tremor group of the International Parkinson's and Movement Disorders Society (IPMDS). 2. Signed informed consent form. Exclusion Criteria: 1. Complicated with brain organic diseases, epilepsy, other mental diseases, family history of dementia, metal devices implanted in the body and any contraindications to TMS; 2. History of craniocerebral surgery; 3. TMS cannot cooperate; 4. TMS-EEG examination artifacts are obvious, or cannot be analyzed due to other technical reasons.
Where this trial is running
Suzhou
- The Second Affiliated Hospital of Soochow University — Suzhou, China (Recruiting)
Study contacts
- Principal investigator: Chun-Feng Liu — Second Affiliated Hospital of Soochow University
- Study coordinator: Chun-Feng Liu, MD
- Email: liuchunfeng@suda.edu.cn
- Phone: +8613606210609
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.