Encora X1 in Daily Life for Essential Tremor

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study follows users of the Encora X1 neurostimulator in a home setting to observe long-term use and satisfaction. Participants are adults with essential tremor who have a prescription for the device and can complete online questionnaires. The study collects information on daily functioning and user experience over up to 36 months without changing the device’s use. It aims to understand real-world patterns, convenience, and potential benefits outside a controlled clinical environment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older and able to comply with all study procedures
* A diagnosis of upper limb Essential Tremor (ET) as determined by clinical history
* A prescription for the Encora X1™
* Must have at least occasional access to a computer, tablet or smartphone, and be able to complete study questionnaires through the participant portal.
* Mentally competent to understand and able to perform written, informed consent (in English only) to participate in the study

Exclusion Criteria:

* Swollen, infected, inflamed areas, or skin eruptions, open wounds, or cancerous lesions of skin at stimulation site
* History of psoriasis, eczema or atopic dermatitis at the stimulation site
* History of peripheral neuropathy in the upper limbs, including carpal tunnel syndrome and diabetic neuropathy
* Pregnant women, or women who plan to become pregnant during their duration of the study
* Use of other External Upper Limb Tremor Stimulation Therapy during the course of the study
* Patient unable to communicate with sponsor/investigator and study staff
* Any other medical conditions or physical or mental impairments that in the sponsor/investigator's opinion would render the participant unsuitable as a candidate for the study.

Where it's running

• Encora Therapeutics
  Boston, Massachusetts, United States Recruiting

Study contacts

• Principal investigator: Ann Marie Murray, MD — West Virginia University
• Study coordinator: Alexis Noyes
• Email: advocates@encoratherapeutics.com
• Phone: 413-529-6728

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.