Clinical trial Recruiting at 1 site Phase 4 Interventional Ages 18 to 70

Using magnetic stimulation to help people quit smoking

Official title: A Pragmatic Feasibility Trial on the Implementation of Transcranial Magnetic Stimulation for Smoking Cessation

Run by Centre for Addiction and Mental Health · NCT06346028 · Data updated 2026-11-12

This study is testing if a new type of brain stimulation can help daily smokers quit smoking by making it easier for them to stop.

Quick facts

PhasePhase 4
Study typeInterventional
Ages18 Years to 70 Years
SexAll
Enrollment40 (estimated)
SponsorCentre for Addiction and Mental Health
Academic / other
Locations1 site (Toronto, Ontario)
StatusRecruiting
StartedMarch 30, 2024
Main results expectedJune 30, 2027
Study endsJune 30, 2028
Registry record updatedMarch 27, 2026
Trial IDNCT06346028 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are daily smokers who are seeking assistance to quit smoking.

Probably not a fit

Patients with certain medical conditions, such as a history of seizures or those with intracranial implants, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the use of repetitive transcranial magnetic stimulation (rTMS) as a non-invasive treatment to assist daily smokers in quitting. Participants will undergo a treatment course consisting of daily rTMS sessions for three weeks, followed by weekly sessions for an additional three weeks. The study aims to assess the feasibility of implementing rTMS in the Nicotine Dependence Clinic at the Center for Addiction and Mental Health in Toronto, Canada, while also gathering participant feedback through surveys and interviews.

Why it matters

Potential benefit: If successful, this treatment could provide a new, effective option for individuals struggling to quit smoking.

How similar studies have gone: Previous studies have shown success with rTMS for smoking cessation, indicating a promising approach to treatment.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria: Patients receiving rTMS

* Smoking cigarettes daily (self-reported)

Inclusion Criteria: Health care providers

* Currently employed as a HCP (physician, social worker, occupational therapist, etc.) at the CAMH NDC
* Involved in the care of at least 1 patient who has received rTMS for smoking cessation

Exclusion Criteria: Patients receiving rTMS

* Have any intracranial implant (e.g., aneurysm clips) or any other metal object within or near the head, excluding the mouth, that cannot be safely removed.
* Pregnant or intending to be pregnant during the study.
* A history of a primary seizure disorder, seizure associated with an intracranial lesion, recurrent seizures related to substance intoxication or withdrawal or recent seizure within the last 6 months.
* Taking any anticonvulsant medication unless it cannot be tapered or discontinued due to risk of clinical safety or destabilization, according to the participant or their referring physician.
* Taking benzodiazepines with dose equivalent or greater than lorazepam 2mg/day unless it cannot be tapered or discontinued due to risk of clinical safety or destabilization, according to the participant or their referring physician.
* Space occupying intracranial lesion.
* Acutely unstable medical, psychiatric, or substance use disorder comorbidity with safety concerns at the discretion of the PI or study physician.

Exclusion Criteria: Health care providers

\- There are no exclusion criteria for HCP Participants

Where it's running

  • Center for Addiction and Mental Health (CAMH)
    Toronto, Ontario, Canada
    Recruiting

Study contacts

  • Principal investigator: Victor Tang, MD, MSc — Center for Addiction and Mental Health
  • Study coordinator: Alexandra S, BScH
  • Email: rtms.smoking@camh.ca
  • Phone: 416-535-8501

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.