Using light therapy to alleviate side effects of breast cancer treatment

Light Therapy to Treat Cancer-related Fatigue, Sleep Problems, Depression and Cognitive Impairment Among Breast Cancer Patients.

Not applicable Interventional Reykjavik University · NCT04418856

This study tests if wearing special glasses that provide bright light can help newly diagnosed breast cancer patients feel less tired, depressed, and have better sleep and thinking during their treatment.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment240 (estimated)
Ages18 Years and up
SexFemale
SponsorReykjavik University Academic / other
Drugs / interventionschemotherapy
Locations1 site (Reykjavik)
Trial IDNCT04418856 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effects of Bright White Light (BWL) therapy on cancer-related side effects in breast cancer patients. It aims to determine whether systematic light exposure can reduce fatigue, depression, sleep disturbances, and cognitive impairment associated with cancer treatment. Participants will wear special glasses that deliver either BWL or Dim White Light (DWL) for 30 minutes each morning during their treatment. The study will include newly diagnosed breast cancer patients undergoing surgery and/or chemotherapy, comparing the effects of the two types of light exposure.

Who should consider this trial

Good fit: Ideal candidates are newly diagnosed breast cancer patients with stages 1 to 3 who are scheduled for surgery and/or chemotherapy.

Not a fit: Patients with advanced stage breast cancer (3B or 4), those with certain psychological conditions, or other significant health impairments may not benefit from this study.

Why it matters

Potential benefit: If successful, this therapy could significantly improve the quality of life for breast cancer patients by reducing debilitating side effects of treatment.

How similar studies have performed: While research on light therapy in cancer patients is limited, preliminary findings suggest potential benefits, making this approach both novel and promising.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Breast cancer Patients: Newly diagnosed patients with stages 1 to 3 breast cancer scheduled to undergo surgery (without chemotherapy) and newly diagnosed patients with stages 1 to 3 breast cancer scheduled to undergo both surgery and chemotherapy.
2. Healthy controls: never received a cancer diagnosis

Exclusion Criteria:

* Stage 3B breast cancer, inflammatory or stage 4 breast cancer; under age 18; pregnancy; pre-existing anemia (Hb \<10gm/dl); history of bipolar disorder or mania (which are contra-indications for BWL treatment); and any other physical or psychological impairments (e.g., sleep disorder diagnosis) which could limit participation.

Where this trial is running

Reykjavik

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Breast CancerCircadian RhythmsFatigueSleep DisturbanceCognitive ImpairmentInflammatory ResponseDepressionBreast cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.