Using antifungal medication to prevent complications after bladder removal surgery.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the use of antifungal prophylaxis with Fluconazole for patients undergoing cystectomy, a complex surgical procedure involving the removal of the urinary bladder and construction of a urinary diversion. The aim is to assess the impact of this prophylaxis on postoperative complications, particularly those related to infections and ileal paralysis. By addressing the risk of fungal infections, which are prevalent in patients undergoing such surgeries, the study seeks to improve patient outcomes and reduce the length of hospital stays.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients 18 years and older
* Willingness to participate in the study and the ability to understand and sign an informed consent
* Indication for performing cystectomy
* The urinary diversion is limited to the ileal conduit

Exclusion Criteria:

* Patients with contraindications to Fluconazole. This includes allergies and treatment with non-pausable medication that in combination is contraindicated
* Patients in active treatment for mycotic infections

Where it's running

• Department of Urology, Rigshospitalet
  Copenhagen, Denmark Recruiting

Study contacts

• Principal investigator: Andreas Røder, MD, PhD, Professor — Urological Research Unit, Department of Urology, Rigshospitalet Blegdamsvej 9, 2100 Copenhagen, Denmark
• Study coordinator: Mie Ynddal, MD
• Email: mie.skjoettgaard.ynddal@regionh.dk
• Phone: +4535456152

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.