Robot-assisted radical cystectomy: effects on blood loss, pain, and transfusions

Prospective Evaluation of Robot-assisted Cystectomies With Regard to Blood Loss, Pain and Transfusion Requirements.

Goethe University · NCT07008261

This trial will test whether robot-assisted bladder removal (radical cystectomy), with or without bladder reconstruction, leads to less blood loss, less postoperative pain, and fewer transfusions for people scheduled for radical cystectomy.

Quick facts

Study typeObservational
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorGoethe University (other)
Locations1 site (Frankfurt am Main)
Trial IDNCT07008261 on ClinicalTrials.gov

What this trial studies

This is a prospective observational study at a tertiary care center that will follow patients undergoing planned robot-assisted radical cystectomy, with or without bladder reconstruction. Researchers will record intraoperative blood loss, postoperative pain scores, and transfusion requirements, using standard clinical measurements and hospital records. Patients with ASA V classification or known coagulation disorders are excluded. The study is non-randomized and aims to describe outcomes associated with the robot-assisted approach in routine clinical practice.

Who should consider this trial

Good fit: Adults scheduled for a planned radical cystectomy at the participating center who do not have ASA class V or a known coagulation disorder would be ideal candidates.

Not a fit: Patients with ASA class V, known coagulation disorders, or those receiving open (non-robotic) cystectomy are unlikely to benefit from this robot-focused observational protocol.

Why it matters

Potential benefit: If successful, the findings could support wider use of robot-assisted cystectomy to reduce blood loss, pain, and the need for transfusions, potentially improving recovery.

How similar studies have performed: Previous comparisons of robot-assisted versus open radical cystectomy have suggested reduced blood loss and transfusion rates in some series, but results are mixed and high-quality prospective data remain limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* planned radical cystectomy

Exclusion Criteria:

* ASA classification V
* Previously known coagulation disorder

Where this trial is running

Frankfurt am Main

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Transfusions, Cystectomy, Blood Loss Requiring Transfusion, Anaemia, Anaemia Postoperative, Pain, Postoperative

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.