Clinical trial Recruiting at 1 site Observational Ages 18 to 70

Using AI to help detect parathyroid glands during thyroid surgery

Official title: Development and Improvement of a Deep Convolutional Neural Network for Detection and Assessing the Perfusion of Parathyroid Gland During Endoscopic Thyroidectomy

Run by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · NCT05869058 · Data updated 2026-11-12

This study is testing a new AI tool to help surgeons find and protect the parathyroid glands during thyroid surgery to improve recovery and reduce the risk of complications.

Quick facts

Study typeObservational
Ages18 Years to 70 Years
SexAll
Enrollment300 (estimated)
SponsorSun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Academic / other
Locations1 site (Guangzhou, Guangdong)
StatusRecruiting
StartedJune 13, 2023
Main results expectedApril 2026
Study endsOctober 2026
Registry record updatedDecember 3, 2025
Trial IDNCT05869058 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients scheduled to undergo endoscopic thyroidectomy.

Probably not a fit

Patients with hyperparathyroidism, hypoparathyroidism, a history of neck surgery, or cervical radiotherapy may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to develop a deep convolutional neural network (DCNN) to assist surgeons in detecting the parathyroid gland (PTG) during endoscopic thyroidectomy. The study will utilize a large sample of endoscopic images to train the DCNN, which will also predict blood perfusion of the PTG by comparing its results to indocyanine green fluorescence angiography. The goal is to improve surgical outcomes and reduce the risk of postoperative hypoparathyroidism by enhancing the detection and preservation of the PTG's blood supply.

Why it matters

Potential benefit: If successful, this approach could significantly reduce the incidence of postoperative hypoparathyroidism in patients undergoing thyroidectomy.

How similar studies have gone: While the use of AI in surgical assistance is emerging, this specific application of DCNN for PTG detection and perfusion assessment is novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* The patients who undergo endoscopic thyroidectomy

Exclusion Criteria:

* hyperparathyroidism
* hypoparathyroidism
* neck surgery history
* cervical radiotherapy history

Where it's running

  • Sun Yat-sen Memorial Hospital
    Guangzhou, Guangdong, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.