Using advanced MRI to improve deep brain stimulation for essential tremor

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to enhance the effectiveness of deep brain stimulation (DBS) for patients with essential tremor by utilizing 7-Tesla MRI technology. The approach focuses on visualizing brain networks connected to the thalamus, which is crucial for DBS electrode placement. By creating detailed structural connectivity maps, the study seeks to individualize DBS settings, potentially leading to better patient outcomes and fewer side effects. The primary goal is to determine if this advanced imaging technique can improve motor symptoms and overall quality of life for patients undergoing DBS.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age \> 18 years
* Idiopathic essential tremor who underwent DBS

Exclusion Criteria:

* Legally incompetent adults
* No written informed consent

Where it's running

• Amsterdam UMC, location AMC
  Amsterdam, North Holland, Netherlands Recruiting

Study contacts

• Study coordinator: Maarten Bot, MD, PhD
• Email: m.bot@amsterdamumc.nl
• Phone: 0031621514048

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Encora X1 in Daily Life for Essential Tremor

  This real-world study tests how the Encora X1 wrist device affects day-to-day activities for adults with essential tremor over three years.

  Recruiting Encora, Inc. · Boston, Massachusetts · NCT07911488

• Intraoperative Microelectrode Recordings with MAVEN vs Standard Equipment

  This study tests whether MAVEN can match the recording data collected during DBS surgery for movement disorders using standard equipment.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07868614

• Microelectrode-based brain stimulation for Parkinson’s and essential tremor

  This early feasibility test checks a new microelectrode-based brain stimulation method in adults with Parkinson’s disease or essential tremor who are already getting deep brain stimulation implants.

  Recruiting Lund University · Lund, Skåne County · NCT07820189

• Non-Invasive Nerve Stimulation for Essential Tremor: Long-Term Safety and Effectiveness

  This study tests whether a non-invasive stimulation device called TAPS helps reduce tremor in adults with essential tremor over a long period.

  Recruiting Ruijin Hospital · Shanghai · NCT07774598

• Low Intensity Focused Ultrasound for Essential Tremor in Adults

  This early-stage, open-label study tests whether repeated low-intensity focused ultrasound can safely and briefly modulate tremor in people with essential tremor.

  Recruiting Early Phase 1 University of California, Los Angeles · Los Angeles, California · NCT07599592

• Closed-loop TMS to reduce tremor

  This trial tries phase-locked transcranial magnetic stimulation (TMS) to reduce tremor in people with essential tremor or Parkinson's disease.

  Recruiting University of Oxford · Oxford, Oxfordshire · NCT07574164

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.