Using a special cast to heal diabetic foot ulcers

Total Contact Soft Cast in Diabetic Foot Ulcers

Not applicable Interventional University of Minnesota · NCT04210089

This study tests whether a special soft cast can help heal diabetic foot ulcers better than regular methods.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Minnesota Academic / other
Locations1 site (Minneapolis, Minnesota)
Trial IDNCT04210089 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness and safety of a total contact soft cast for treating diabetic foot ulcers compared to traditional offloading methods. Participants will receive a customized cast that includes various layers of materials designed to support the healing process. The study will also assess patient compliance, tolerance, and ease of use of the cast, with some patients potentially using a removable cam boot. Weekly follow-ups will be conducted to monitor progress and adjust treatment as necessary.

Who should consider this trial

Good fit: Ideal candidates are adults with diabetic foot ulcers who can comply with weekly follow-up visits.

Not a fit: Patients with allergies to key materials used in the cast or those unable to consent or comply with treatment may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could provide a more effective and comfortable treatment option for patients with diabetic foot ulcers.

How similar studies have performed: While there have been various approaches to treating diabetic foot ulcers, the specific use of a total contact soft cast is less commonly studied, making this a novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

\- Any adult with a diabetic foot ulcer

Exclusion Criteria:

* Allergy to Calamine or Zinc oxide
* Inability to have leg wrapped
* Inability to be seen weekly or as needed
* Unable or unwilling to consent
* Prisoners
* Persons lacking capacity to consent

Where this trial is running

Minneapolis, Minnesota

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Diabetic Foot UlcerDiabetes MellitusFoot UlcerFoot Ulcer, DiabeticUlcerUlcer FootUlcer, LegAnkle Ulcer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.