Using a robotic system to adjust knee surgery in real-time

ROSA Knee Intraoperative Planning Flexibility on Japan Preferred Surgical Technique, A Single Center Prospective Study

Observational Zimmer Biomet · NCT05966519

This study is testing if a robotic system can help make real-time adjustments during knee surgery to improve outcomes for patients getting total knee replacements.

Quick facts

Study typeObservational
Enrollment80 (estimated)
Ages20 Years and up
SexAll
SponsorZimmer Biomet Industry-sponsored
Locations1 site (Fukuoka, Fukuoka)
Trial IDNCT05966519 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the effectiveness of the ROSA Knee System, an orthopedic surgical assist robot, in providing intraoperative adjustments during total knee arthroplasty (TKA) based on real-time feedback from soft tissue conditions. A total of 80 patients will be enrolled at Kyushu University Hospital, with a follow-up period of two years to assess surgical outcomes. The study will document the accuracy of the robot's adjustments and their alignment with the surgeon's preferred techniques, focusing on various endpoints including kinematic analysis and patient-reported outcomes.

Who should consider this trial

Good fit: Ideal candidates are adults aged 20 and over who are scheduled for total knee arthroplasty using the ROSA Knee System.

Not a fit: Patients with serious bone defects, active infections, or other significant health issues that could compromise surgery outcomes may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance the precision of knee surgeries, leading to improved patient outcomes and satisfaction.

How similar studies have performed: While robotic assistance in orthopedic surgery is gaining traction, this specific approach to intraoperative adjustments based on real-time feedback is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 20 years and over
* Skeletally matured
* Decision to have Total Knee Arthroplasty with ROSA Knee System being made independently and prior to recruitment into study
* Willing and able to complete scheduled follow-up evaluations as described in the study protocol
* Has participated in the informed consent process and is willing and able to sign an Institutional Review Board (IRB)/Ethics Committee (EC) approved informed consent form

Exclusion Criteria:

* Has serious bone defect(s), which require(s) metallic augment, synthetic bone or allograft
* Is septic, has an active infection or has osteomyelitis at the affected joint
* Has vascular insufficiency, muscular atrophy at the implant site or neuromuscular disease which might jeopardize the outcome of the surgery
* Has any concomitant disease which is likely to jeopardize the functioning or success of the implant
* Is known to be pregnant
* Is a prisoner, known alcohol or drug abuser or mentally incompetent or unable to understand what participation in this study entails
* Has a known sensitivity or allergy to one or more of the implanted materials

Where this trial is running

Fukuoka, Fukuoka

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Osteo Arthritis KneeRheumatoid Arthritis
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.