GenAI-assisted RA bone erosion risk and DMARD choice
Official title: Prospective Evaluation of Generative AI-Augmented Clinical Decision-Making for Rheumatoid Arthritis Bone Erosion Risk (RABER) Assessment and DMARD Selection in Routine Care
Run by Guang'anmen Hospital of China Academy of Chinese Medical Sciences · NCT07914907 · Data updated 2026-11-12
This study tests whether GenAI-based decision support can help doctors assess rheumatoid arthritis bone erosion risk and pick DMARDs for newly diagnosed inpatients.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Guang'anmen Hospital of China Academy of Chinese Medical Sciences Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | March 1, 2026 |
| Main results expected | October 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | November 4, 2026 |
| Trial ID | NCT07914907 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are adults with newly diagnosed RA meeting established classification criteria and admitted as inpatients during the study period.
✕Probably not a fit
Patients with incomplete data or those whose RA diagnosis is later ruled out may not benefit from GenAI-assisted recommendations.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In this prospective, single-arm study, physicians use GenAI-assisted clinical decision support to help determine RA bone erosion risk and select DMARDs during routine inpatient care. The study focuses on newly diagnosed RA patients admitted to Guang’anmen Hospital in Beijing. Researchers will document physicians’ initial risk assessments and treatment choices with and without GenAI input to evaluate feasibility and potential impact in real-world practice.
Why it matters
Potential benefit: If successful, GenAI support could streamline risk assessment and DMARD selection, potentially improving treatment appropriateness and outcomes.
How similar studies have gone: Previous work with GenAI in clinical decision support suggests potential benefits, but real-world effectiveness in RA care is still being explored.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Newly diagnosed RA patients meeting American College of Rheumatology / European League Against Rheumatism 2010 classification criteria * Consecutive inpatients admitted during study period Exclusion Criteria: * Patients subsequently determined not to have RA * Incomplete clinical data preventing risk or treatment assessment
Where it's running
-
Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Beijing, Beijing Municipality, China Recruiting
Study contacts
- Study coordinator: Quan Jiang, MD
- Email: doctorjq@126.com
- Phone: 010-88001942
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Pain patterns in rheumatic diseases: see if pain works differently in patients and healthy people
This observational study tests how pain is experienced and measured in people with rheumatic diseases compared with healthy volunteers.
-
Telitacicept for difficult-to-treat rheumatoid arthritis
This study tests whether adding telitacicept to standard therapy helps adults with hard-to-treat rheumatoid arthritis see better control of their symptoms.
-
PTC844 in people with active rheumatoid arthritis
This study tests whether PTC844 is safe and how it behaves in the body compared with placebo for people with active rheumatoid arthritis.
-
First-in-human test of CND319 in healthy people and people with rheumatic diseases
This early study tests whether CND319 is safe and tolerable and whether it shows any signs of activity in healthy adults and in people with rheumatoid arthritis or Sjogren's syndrome.
-
IV sarilumab for adults with rheumatoid arthritis
This study tests IV sarilumab to see how it works and how safe it is for adults with moderately to severely active rheumatoid arthritis, with or without certain standard arthritis medicines.
-
Tipmed Shoulder Prosthesis PMCF: safety and outcomes after shoulder replacement
This PMCF study tests the safety and function of the Tipmed shoulder prosthesis in adults undergoing reverse shoulder or hemiarthroplasty in real-world practice.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.