Using a nerve block to relieve acute back pain in the emergency department
Official title: Erector Spinae Plane Block for Acute Back Pain in the Emergency Department
Run by Rush University Medical Center · NCT06745453 · Data updated 2026-11-12
This study is testing if a nerve block can help adults with acute low back pain in the emergency department feel better and recover faster compared to a placebo.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 62 (estimated) |
| Sponsor | Rush University Medical Center Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Status | Recruiting |
| Started | February 3, 2025 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | March 12, 2026 |
| Trial ID | NCT06745453 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older presenting with isolated low back pain for less than 6 weeks.
✕Probably not a fit
Patients who do not speak English or Spanish, are incarcerated, pregnant, allergic to amide-type local anesthetics, or have critical illnesses may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to evaluate the effectiveness of the erector spinae plane block (ESPB) in reducing pain for adults with low back pain who visit the emergency department. Participants will receive either the ESPB or a placebo injection and will report their pain levels for up to 120 minutes, as well as their pain, disability, and return to work status after 7 days. The study seeks to determine both short-term and longer-term benefits of the ESPB compared to a non-active treatment.
Why it matters
Potential benefit: If successful, this approach could provide significant pain relief and improve recovery outcomes for patients with acute low back pain.
How similar studies have gone: Other studies have shown promising results with similar nerve block techniques, suggesting potential effectiveness for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults (age ≥18 years) presenting to the emergency department with isolated low back pain present less than 6 total weeks. Exclusion Criteria: * Do not speak English or Spanish as a primary language * Are incarcerated * Have a known pregnancy * Are allergic to amide-type local anesthetics * Are unable to tolerate positioning for the procedure * Have a critical illness precluding the ability to perform the procedure.
Where it's running
-
Rush University Medical Center
Chicago, Illinois, United States Recruiting
Study contacts
- Principal investigator: Michael Gottlieb, MD — Rush University Medical Center
- Study coordinator: Aylin Ornelas Loredo, MMS
- Email: aylin_a_ornelasloredo@rush.edu
- Phone: 312-563-0645
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
A novel multi angular isometric lumbar exercise for chronic low back pain
This trial tests MAILE, a new lumbar exercise method, to see if it helps adults with nonspecific chronic low back pain more than standard lumbar stabilization and core exercises.
-
Pain catastrophizing, fear of movement, and activity in postmenopausal women with chronic low back pain
This observational study looks at how negative pain thoughts and fear of moving relate to how active postmenopausal women with long‑standing low back pain are.
-
Analgesia boost from adding a sacral submultifidus block to SIJ injection
This study tests whether adding a sacral submultifidus block to a standard image-guided sacroiliac joint injection provides better pain relief and function for adults with chronic SIJ‑related pain.
-
Telerehabilitation after spine surgery
This trial tests different ways of delivering post-operative instructions to people who had spinal decompression surgery to see how it affects recovery and healthcare use.
-
How patient education helps people with chronic musculoskeletal pain stick to home exercise for pain relief
A structured patient education program is tested to see if it helps people with chronic low back pain, knee osteoarthritis, and shoulder problems stick with their home exercise plan to relieve pain.
-
Core endurance vs segmental stabilization for low back pain in recreational athletes
This trial tests whether core endurance exercises or segmental stabilization exercises better help recreational athletes with non-specific low back pain.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.