Using a nerve block for pain control in open heart surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of a bilateral nerve block using ropivacaine as part of a multimodal analgesia regimen for patients undergoing open-heart surgery. Participants will be randomly assigned to receive either the nerve block or a saline placebo, and their pain and nausea levels will be assessed at multiple time points post-surgery. The study aims to determine if the nerve block can improve pain management outcomes compared to standard care. It is conducted at Richard M. Ross Hospital - The Ohio State University Medical Center, following strict institutional guidelines.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult male or female patients aged \> 18
* Undergoing primary cardiac surgery requiring sternotomy
* Able to provide a signed written informed consent
* Able to speak, read, and write in English
* American Society of Anesthesiologists (ASA) physical status I-IV

Exclusion Criteria:

* Any documented cognitive or psychological disorders that, in the opinion of the principal investigator, can interfere with the patients' pain perception
* Diabetes Mellitus with documented neuropathic pain
* Vulnerable populations: pregnant females, prisoners, breast feeding
* Contraindication to nerve block: local infections, bleeding disorders, chest wall deformity, allergy to local anesthetic or dexamethasone
* Previous cardiac surgery
* Previous history of chronic pain diseases requiring consistent analgesic therapy for at least 1 month prior to surgery
* Presence of any medical condition that, in the opinion of the principal investigator, should exclude the patient from the study
* BMI ≥ 40 kg/m2

Where it's running

• The Ohio State University Wexner Medical Center
  Columbus, Ohio, United States Recruiting

Study contacts

• Study coordinator: Alberto A Uribe
• Email: alberto.uribe@osumc.edu
• Phone: 6142930775

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.