New Generation Therapies for Suicide: Refining Brief Cognitive Behavioral Therapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers at Ohio State University will use a SMART design to optimize Brief Cognitive Behavioral Therapy (BCBT) for suicide prevention. All participants begin with 4 BCBT sessions and weekly assessments, plus 4 weeks of ecological momentary assessment and digital phenotyping to track fluctuations in suicidality. The trial aims to identify which sequences and doses of BCBT components most effectively lower suicide risk. The study is funded by The Jordan Elizabeth Harris Foundation and involves outpatient treatment at the Columbus, Ohio site. This design allows adjustments based on each participant's response to initial therapy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years of age or older; suicidal ideation (assessed with the SSI) and/or suicidal behavior within the past month (assessed with the SITBI-R), psychiatric hospitalization for elevated suicide risk within the past month, and/or SCS-R total score \>21; eligibility to understand and speak the English language; ability to complete the informed consent process

Exclusion Criteria:

* impaired mental status that precludes the ability to provide informed consent (e.g., intoxication, psychosis, mania) and/or a medical or psychiatric condition that precludes the ability to engage in outpatient therapy

Where it's running

• Department of Psychiatry and Behavioral Health
  Columbus, Ohio, United States Recruiting

Study contacts

• Principal investigator: Melanie Bozzay, PhD — Ohio State University
• Study coordinator: Anna Crouser, MSW, LSW
• Email: anna.crouser@osumc.edu
• Phone: 614-293-2554

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Videoconference Brief Cognitive Behavioral Therapy for mood disorders at high suicide risk

  This study tests a short online CBT program to help people with mood disorders who are at high risk of suicide, and compares inflammatory biomarkers between groups.

  Recruiting Asan Medical Center · Seoul · NCT07857291

• MRI plus diffusion and CEST imaging to map liver cancer and its immune environment

  This study tests whether adding an extra MRI sequence can help see how the liver cancer microenvironment changes and relate those changes to immune activity in patients with hepatocellular carcinoma.

  Recruiting Tongji Hospital · Wuhan, Hubei · NCT07838415

• Brief Cognitive Behaviour Therapy to Prevent Suicide Reattempts in Swedish Psychiatric Inpatient Care

  This study tests whether four brief CBT sessions can be delivered during a psychiatric hospital stay to help adults who recently attempted suicide or are at high risk see if the treatment works and is easy to use in routine care.

  Recruiting Karolinska Institutet · Stockholm · NCT07567885

• Repeated PSMA PET scans to monitor treatment response in clinically significant prostate cancer.

  This project will test whether doing a PSMA PET/CT before treatment and again after treatment (or at early PSA rise) helps track response in people with newly diagnosed clinically significant (Gleason ≥7) prostate cancer.

  Recruiting at 9 sites Xijing Hospital · Lanzhou, Gansu and 8 other locations · NCT07553780

• Safety Planning Intervention rollout in Swedish psychiatric services to prevent suicide

  This project will try a single-session Safety Planning Intervention with adults who present to psychiatric emergency or inpatient units with suicidal thoughts or attempts to see if it reduces suicide-related emergency visits and hospitalizations.

  Recruiting at 2 sites Region Skane · Helsingborg, Skåne County and 3 other locations · NCT07469917

• Using genetics and smartphone data to predict and prevent repeat suicide attempts

  This project will try to combine genetic tests and people’s digital behavior to predict which individuals with a past suicide attempt may be at higher risk of trying again.

  Recruiting Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz · Madrid, Madrid · NCT07422090

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.