Understanding tobacco and cannabis use among young adults
Official title: The Impact of Cannabis and Tobacco/Nicotine Product Co-use in Young Adults: Prospective Cessation Evaluation and Substitution
Run by Medical University of South Carolina · NCT06239350 · Data updated 2026-11-12
This study looks at how using cannabis affects young adults aged 18-25 who are trying to quit tobacco, while they receive support for their quit attempt over 12 weeks.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 25 Years |
| Sex | All |
| Enrollment | 350 (estimated) |
| Sponsor | Medical University of South Carolina Academic / other |
| Locations | 1 site (Charleston, South Carolina) |
| Status | Recruiting |
| Started | May 13, 2024 |
| Main results expected | October 1, 2027 |
| Study ends | January 3, 2028 |
| Registry record updated | November 4, 2026 |
| Trial ID | NCT06239350 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are young adults aged 18-25 who use both tobacco products and cannabis regularly.
✕Probably not a fit
Patients who are not interested in quitting tobacco or who have significant medical or psychiatric issues may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project aims to explore the relationship between tobacco/nicotine and cannabis use among young adults aged 18-25 during a quit attempt for tobacco products. Participants will receive a 12-week cessation treatment for tobacco/nicotine while their cannabis use patterns are monitored. The study employs a behavioral economics framework to evaluate how cannabis co-use impacts nicotine cessation efforts. All procedures are conducted remotely, eliminating the need for in-person visits.
Why it matters
Potential benefit: If successful, this study could lead to improved cessation strategies for young adults who use both tobacco and cannabis.
How similar studies have gone: While previous studies have explored tobacco cessation, this approach focusing on nicotine-cannabis co-use is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Between the ages of 18 and 25 years old * Must use at least one nicotine or tobacco product (nicotine vaping and/or cigarettes) on at least 20 out of the past 30 days for at least the past 3 months * Must express interest in nicotine cessation (all products) * Must submit a positive instant-read cotinine sample prior to enrollment * Must report use of cannabis on at least 10 out of the past 30 days * Must submit a positive instant-read cannabinoid test prior to enrollment * Must be able to provide informed consent Exclusion Criteria: * Any significant or acutely unstable medical, psychiatric, or substance use problem that would contraindicate research, interfere with safety, compromise data integrity, or preclude consistent study participation * Pregnant (self-report) or trying to become pregnant * Self-reported use of medications with smoking cessation efficacy * Immediate interest in cannabis cessation or treatment
Where it's running
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Medical University of South Carolina - Charleston
Charleston, South Carolina, United States Recruiting
Study contacts
- Study coordinator: Elizabeth Chapman
- Email: chapmanb@musc.edu
- Phone: 864.898.2992
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.