Understanding the connection between heart and brain in acute ischemic stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the relationship between heart conditions and acute ischemic stroke, focusing on how heart attacks can lead to strokes and vice versa. It aims to improve the accuracy of diagnosing heart attacks in patients who have suffered a stroke by utilizing cardiovascular MRI and other assessments. The study will involve collecting blood and urine samples to analyze the underlying mechanisms of these conditions. By identifying the causes of stroke more precisely, the research seeks to enhance treatment strategies and reduce the risk of recurrence.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Informed consent as documented by signature.
* Age: ≥ 18 and \< 86 years.
* Acute ischemic stroke with symptom onset within 12 hours before admission to hospital.
* Diagnosis of acute ischemic stroke with MRI with diffusion restriction as seen on diffusion weighted imaging.

Exclusion Criteria:

* Pregnancy. A negative pregnancy test upon admission is required for all women with child-bearing potential.
* Standard contraindication for performing MRI.
* Severe renal failure (GFR \<40).

Where it's running

• Bern University Hospital - Inselspital
  Bern, Canton of Bern, Switzerland Recruiting

Study contacts

• Study coordinator: Simon Jung, PD Dr. med.
• Email: simon.jung@insel.ch
• Phone: +41 31 632 79 56

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.