Understanding reading difficulties in stroke survivors and older adults
Official title: ReadMap: Reading in Stroke Alexia and Typical Aging
Run by Georgetown University · NCT06700005 · Data updated 2026-11-12
This study looks at how reading problems, called alexia, affect stroke survivors and older adults to see how their brains work and how we can help them better.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Georgetown University Academic / other |
| Locations | 1 site (Washington D.C., District of Columbia) |
| Status | Recruiting |
| Started | January 12, 2023 |
| Main results expected | August 31, 2028 |
| Study ends | August 31, 2028 |
| Registry record updated | November 21, 2024 |
| Trial ID | NCT06700005 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include stroke survivors and older adults aged 18 and above who learned English at 8 years or younger.
✕Probably not a fit
Patients with other brain disorders, severe psychiatric conditions, or significant sensory impairments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the cognitive and brain mechanisms underlying reading difficulties, known as alexia, in stroke survivors and typical older adults. Participants will undergo a series of tests assessing their reading, speech, language, and cognitive abilities, with some also participating in MRI scans to explore brain function. The study aims to enhance the understanding of how stroke and aging affect reading capabilities, potentially leading to improved diagnostic and therapeutic strategies for those affected by alexia.
Why it matters
Potential benefit: If successful, this study could lead to better diagnosis and treatment options for individuals suffering from reading difficulties due to stroke.
How similar studies have gone: While studies on stroke and cognitive impairments exist, this specific focus on alexia in stroke survivors and older adults is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: Stroke Survivors: * Age \>= 18 * Learned English at 8 years or younger * Brain injury resulting from stroke Controls: * Age \>= 18 * Learned English at 8 years or younger Exclusion criteria for all groups: * History of other brain disorder that could interfere with our ability to interpret results (e.g., Multiple sclerosis, dementia, head injury causing loss of consciousness) * Severe psychiatric condition that would interfere with participation in the study * History of diagnosed learning disorder * Hearing or vision loss that interferes with performance on behavioral tests even after correction with glasses/hearing aids. * Inability to follow study procedures despite maximal support Additional exclusion criteria for MRIs: * Presence of metal in the body that is incompatible with MRI * Pregnancy * Claustrophobia
Where it's running
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Georgetown University Medical Center
Washington D.C., District of Columbia, United States Recruiting
Study contacts
- Principal investigator: Peter Turkeltaub, MD,PhD — Georgetown University; MedStar National Rehabilitation Hospital
- Study coordinator: Alycia Laks, MS, CCC-SLP
- Email: crlab@georgetown.edu
- Phone: 202-687-5205
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Digital speech-therapy app Zenicom for subacute post-stroke aphasia in Korean speakers
This trial will try the Zenicom digital speech-therapy app alongside conventional therapy to see if it helps Korean adults with aphasia after a recent (within 3 months) stroke.
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This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.
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TMS plus language therapy to improve word-finding after left-hemisphere stroke
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.