Understanding movement disorders and their impact on families

Natural History Protocol for Movement Disorders

Observational National Institutes of Health Clinical Center (CC) · NCT05413291

This study is gathering information from people with movement disorders like Parkinson's and their families to help improve future treatments.

Quick facts

Study typeObservational
Enrollment4000 (estimated)
Ages2 Years to 100 Years
SexAll
SponsorNational Institutes of Health Clinical Center (CC) NIH
Locations1 site (Bethesda, Maryland)
Trial IDNCT05413291 on ClinicalTrials.gov

What this trial studies

This observational study aims to collect data on individuals with various movement disorders, including Parkinson's disease, as well as their family members. Participants aged 2 years and older will undergo screening, including physical exams and review of existing medical images. The collected data will be used to support future research aimed at improving treatment options for movement disorders. No experimental interventions will be conducted; instead, the focus is on gathering information as part of standard care.

Who should consider this trial

Good fit: Ideal candidates include individuals aged 2 and older with a movement disorder or those who are family members of affected individuals.

Not a fit: Patients under 2 years old will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and treatment options for movement disorders.

How similar studies have performed: Other studies have shown success in understanding movement disorders through observational data collection, making this approach both relevant and valuable.

Eligibility criteria

Show full inclusion / exclusion criteria
* INCLUSION CRITERIA:

In order to be eligible to participate in this study, an individual must meet all of the following criteria:

* Stated willingness to comply with all study procedures and availability for the duration of the study
* Male or female, aged 2 and above
* Either one of these:

  * Have or suspected to have a diagnosis of a movement disorder.
  * Family member of someone who has or is suspected of having a diagnosis of a movement disorder.
* Ability of subject or Legally Authorized Representative (LAR) to understand and the willingness to sign a written informed consent document.

EXCLUSION CRITERIA:

An individual who meets the following criteria will be excluded from participation in this study:

-Being \< 2 years old.

Where this trial is running

Bethesda, Maryland

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Movement DisorderTremorParkinson's DiseaseNatural History
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.