Understanding induced membrane properties in bone reconstruction
Induced Membrane Properties in Children and Adults
This study is testing how special membranes formed during a bone reconstruction technique can help improve healing in both children and adults.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 9 Months to 60 Years |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens) |
| Trial ID | NCT04246944 on ClinicalTrials.gov |
What this trial studies
This study investigates the properties of induced membranes formed during the Masquelet technique for bone reconstruction in critical sized defects. It aims to characterize the angiogenesis and osteogenic properties of these membranes in both children and adults. By analyzing the induced membranes, the study seeks to enhance the understanding of their role in bone healing and improve surgical outcomes. Participants will include patients treated at CHU Amiens-Picardie who are undergoing this specific reconstruction technique.
Who should consider this trial
Good fit: Ideal candidates are patients aged 9 months to 60 years who are treated for bone critical sized defects using the induced membrane reconstruction technique.
Not a fit: Patients who are managed by other reconstruction techniques or those who are pregnant, nursing, or under guardianship may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved techniques for bone healing and reconstruction in patients with critical sized defects.
How similar studies have performed: While the Masquelet technique has been used in practice, the specific characterization of induced membrane properties is a novel approach that has not been extensively studied.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients treated at CHU Amiens-Picardie for bone critical sized defect treated using the induced membrane reconstruction technique. * patients from 9 months to 60 years old Exclusion Criteria: * Patients managed by another reconstruction technique for critical sized defect * Patients under guardianship, curators or deprived of liberty. * Pregnant and nursing women. * Patients who refused to participate in the study and to sign informed consent.
Where this trial is running
Amiens
- CHU Amiens — Amiens, France (Recruiting)
Study contacts
- Principal investigator: Céline Klein, MD — CHU Amiens
- Study coordinator: Céline Klein, MD
- Email: klein.celine@chu-amiens.fr
- Phone: (33)322087571
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.