Understanding how aging affects blood vessel health and heart disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the role of vascular senescence and DNA damage in the development of coronary artery disease. It aims to explore how chronological aging and environmental factors contribute to vascular deterioration and atherosclerosis. By analyzing biomarkers related to DNA damage and cellular senescence, the study seeks to identify potential therapeutic targets to mitigate the effects of vascular aging. Participants will include patients with various forms of acute coronary syndromes and stable angina.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with acute coronary syndromes (unstable angina, non-ST segment elevation myocardial infarction (NSTEMI), ST segment elevation myocardial infarction (STEMI))
* stable angina
* non-angiographically significant coronary diseases recovered for elective diagnostic or interventional procedures

Exclusion Criteria:

* cardiac shock
* congestive heart failure
* end stage renal diseases
* coronary artery bypass graft
* active cancer

Where it's running

• ASST GOM Niguarda
  Milan, Lombardy, Italy Recruiting

Study contacts

• Study coordinator: Jonica Campolo, MSc
• Email: jonica.campolo@ospedaleniguarda.it
• Phone: +39026444

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.