Predicting vasopressor needs after anesthesia in elective on-pump CABG using dynamic arterial elastance

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, observational study will measure dynamic arterial elastance (EaDyn) from pulse pressure variation and stroke volume variation before anesthesia and at 1, 3, and 5 minutes after induction in adults undergoing elective on-pump CABG. It will assess whether EaDyn can predict the requirement for vasopressor treatment. No additional interventions are performed beyond standard care, and data are collected from patients with arterial catheter monitoring on mechanical ventilation. The aim is to identify a potentially useful hemodynamic predictor to guide perioperative management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥18 years.
2. Patients undergoing elective cardiac surgery with cardiopulmonary bypass (on-pump).
3. Patients with arterial catheter monitoring.
4. Patients receiving mechanical ventilation.

Exclusion Criteria:

1. Arrhythmia (e.g., atrial fibrillation).
2. Severe aortic regurgitation.
3. Spontaneous breathing.
4. Low tidal volume.
5. Emergency surgery.
6. Off-pump cardiac surgery (cardiac surgery performed without cardiopulmonary bypass).

Where it's running

• Gaziantep University Hospital
  Gaziantep, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Elzem Şen, Md
• Email: drelzemsen@gmail.com
• Phone: +905327842151

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.