Clinical trial Recruiting at 1 site Observational Ages 18 and up

Understanding hand function issues in systemic sclerosis

Official title: Hand Function Impairment in Systemic Sclerosis: Outcomes, Mechanisms and Experience (HANDSOME) Study

Run by UMC Utrecht · NCT06133244 · Data updated 2026-11-12

This study looks at how systemic sclerosis affects hand function in patients to see what causes problems and how to better manage them.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment300 (estimated)
SponsorUMC Utrecht
Academic / other
Locations1 site (Utrecht)
StatusRecruiting
StartedApril 19, 2024
Main results expectedApril 2028
Study endsApril 2028
Registry record updatedMay 28, 2024
Trial IDNCT06133244 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults over 18 years diagnosed with systemic sclerosis.

Probably not a fit

Patients with diabetic cheiroarthropathy or Dupuytren's disease may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients with systemic sclerosis (SSc) to explore the outcomes, mechanisms, and experiences related to hand function impairment. It aims to investigate the processes leading to limitations in hand function, particularly due to contractures, which affect a significant number of patients. The study will utilize imaging, blood samples, functional tests, and physical examinations to gather comprehensive data over time. By following a longitudinal cohort, the researchers hope to gain insights that could inform better management strategies for affected individuals.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and management of hand function impairments in systemic sclerosis patients.

How similar studies have gone: While there have been studies on systemic sclerosis, this specific focus on hand function impairment and its mechanisms is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \> 18 years

Exclusion Criteria:

* Patients with diabetic cheiroarthropathy and Dupuytren's disease, based on expert opinion

Where it's running

  • UMC Utrecht
    Utrecht, Netherlands
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.