Understanding hand function issues in systemic sclerosis
Hand Function Impairment in Systemic Sclerosis: Outcomes, Mechanisms and Experience (HANDSOME) Study
This study looks at how systemic sclerosis affects hand function in patients to see what causes problems and how to better manage them.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | UMC Utrecht Academic / other |
| Locations | 1 site (Utrecht) |
| Trial ID | NCT06133244 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on patients with systemic sclerosis (SSc) to explore the outcomes, mechanisms, and experiences related to hand function impairment. It aims to investigate the processes leading to limitations in hand function, particularly due to contractures, which affect a significant number of patients. The study will utilize imaging, blood samples, functional tests, and physical examinations to gather comprehensive data over time. By following a longitudinal cohort, the researchers hope to gain insights that could inform better management strategies for affected individuals.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years diagnosed with systemic sclerosis.
Not a fit: Patients with diabetic cheiroarthropathy or Dupuytren's disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of hand function impairments in systemic sclerosis patients.
How similar studies have performed: While there have been studies on systemic sclerosis, this specific focus on hand function impairment and its mechanisms is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 18 years Exclusion Criteria: * Patients with diabetic cheiroarthropathy and Dupuytren's disease, based on expert opinion
Where this trial is running
Utrecht
- UMC Utrecht — Utrecht, Netherlands (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.