Understanding gastric issues in patients with enlarged stomach blood vessels
Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias
This study is trying to see how often stomach problems like pain and nausea happen in adults with a condition called Gastric Antral Vascular Ectasia and how these issues relate to how well their stomachs work.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | 19 Years and up |
| Sex | All |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Rochester, Minnesota) |
| Trial ID | NCT06306963 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the prevalence of gastric motor dysfunction and upper gastrointestinal symptoms in patients diagnosed with Gastric Antral Vascular Ectasia (GAVE). Participants over 18 years old with endoscopic evidence of GAVE will undergo a Gastric Emptying Breath Test to assess stomach function and correlate it with symptoms like abdominal pain and nausea. The study seeks to enhance understanding of how often these symptoms occur in relation to the condition, thereby contributing valuable data to the medical community.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 with confirmed Gastric Antral Vascular Ectasia and no other significant health issues.
Not a fit: Patients with severe liver disease, end-stage renal disease, or other significant metabolic disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis and management strategies for patients suffering from GAVE and related gastrointestinal symptoms.
How similar studies have performed: While this study focuses on a specific condition, similar observational studies have successfully identified correlations between gastrointestinal symptoms and underlying vascular conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients \>18 years of age with endoscopic evidence of Gastric Antral Vascular Ectasia. * Willingness to participate in the study * Capacity to provide informed consent. * No evidence of organic, systemic, or metabolic disease (e.g. diabetes mellitus) to explain the symptoms on routine investigations Exclusion Criteria: * Patients with transfusion dependent blood loss. * Patients with severe decompensated liver disease. * Patients with end stage renal disease. * Presence of other diseases (structural or metabolic) which could interfere with interpretation of the study results. * Pregnant or lactating women. * Patients who have not had a CBC and differential blood draw completed within the last six months. * Current heavy alcohol use.
Where this trial is running
Rochester, Minnesota
- Mayo Clinic — Rochester, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Xiao Jing Wang, MD — Mayo Clinic
- Study coordinator: Taylor N Hines
- Email: hines.taylor@mayo.edu
- Phone: 507-538-9959
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.