Understanding gastric issues in patients with enlarged stomach blood vessels
Official title: Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias
Run by Mayo Clinic · NCT06306963 · Data updated 2026-11-12
This study is trying to see how often stomach problems like pain and nausea happen in adults with a condition called Gastric Antral Vascular Ectasia and how these issues relate to how well their stomachs work.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 19 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Rochester, Minnesota) |
| Status | Recruiting |
| Started | March 22, 2024 |
| Main results expected | December 1, 2026 |
| Study ends | December 1, 2026 |
| Registry record updated | October 26, 2026 |
| Trial ID | NCT06306963 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 with confirmed Gastric Antral Vascular Ectasia and no other significant health issues.
✕Probably not a fit
Patients with severe liver disease, end-stage renal disease, or other significant metabolic disorders may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate the prevalence of gastric motor dysfunction and upper gastrointestinal symptoms in patients diagnosed with Gastric Antral Vascular Ectasia (GAVE). Participants over 18 years old with endoscopic evidence of GAVE will undergo a Gastric Emptying Breath Test to assess stomach function and correlate it with symptoms like abdominal pain and nausea. The study seeks to enhance understanding of how often these symptoms occur in relation to the condition, thereby contributing valuable data to the medical community.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis and management strategies for patients suffering from GAVE and related gastrointestinal symptoms.
How similar studies have gone: While this study focuses on a specific condition, similar observational studies have successfully identified correlations between gastrointestinal symptoms and underlying vascular conditions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients \>18 years of age with endoscopic evidence of Gastric Antral Vascular Ectasia. * Willingness to participate in the study * Capacity to provide informed consent. * No evidence of organic, systemic, or metabolic disease (e.g. diabetes mellitus) to explain the symptoms on routine investigations Exclusion Criteria: * Patients with transfusion dependent blood loss. * Patients with severe decompensated liver disease. * Patients with end stage renal disease. * Presence of other diseases (structural or metabolic) which could interfere with interpretation of the study results. * Pregnant or lactating women. * Patients who have not had a CBC and differential blood draw completed within the last six months. * Current heavy alcohol use.
Where it's running
-
Mayo Clinic
Rochester, Minnesota, United States Recruiting
Study contacts
- Principal investigator: Xiao Jing Wang, MD — Mayo Clinic
- Study coordinator: Taylor N Hines
- Email: hines.taylor@mayo.edu
- Phone: 507-538-9959
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.