Ultra-rapid blastocyst vitrification for donor oocyte cycles
Official title: Clinical Validation of Ultra-rapid Blastocyst Vitrification: a Randomized Pilot Study in Oocyte Donation Cycles
Run by Fundacion Dexeus · NCT07556601 · Data updated 2026-11-12
This pilot study tests whether ultra-rapid blastocyst vitrification is safe and feasible for donor oocytes compared with the standard method.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 50 Years |
| Sex | Women only |
| Enrollment | 80 (estimated) |
| Sponsor | Fundacion Dexeus Academic / other |
| Locations | 2 sites (Barcelona and 1 other locations) |
| Status | Recruiting |
| Started | June 1, 2026 |
| Main results expected | December 2027 |
| Study ends | March 2028 |
| Registry record updated | June 30, 2026 |
| Trial ID | NCT07556601 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women receiving donor oocytes with blastocysts suitable for cryopreservation.
✕Probably not a fit
Cycles not reaching the blastocyst stage or those using PGT may not benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized, interventional pilot study compares an ultra-rapid blastocyst vitrification protocol to the standard vitrification approach in recipients of donor oocytes. The main focus is on safety, feasibility, and preliminary clinical performance, including post-warming viability and potential impacts on clinical outcomes. The study builds on existing vitrification methods and investigates whether faster exposure to cryoprotectants and an additional embryological step affect outcomes. It is designed as an initial step before broader clinical use, to identify any safety concerns or practical workflow implications. The trial is conducted at a single leading center in Barcelona with two listed locations, under the lead sponsor Fundacion Dexeus.
Why it matters
Potential benefit: If successful, ultra-rapid vitrification could streamline laboratory workflow and potentially improve embryo survival and clinical outcomes after transfer.
How similar studies have gone: Clinical data on ultra-rapid blastocyst vitrification are limited, making this pilot study an exploratory step with uncertain similarity to prior work.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Recipients of donor oocytes * Blastocysts suitable for cryopreservation Exclusion Criteria: * Cycles involving PGT * Cycles not reaching blastocyst stage.
Where it's running
-
Hospital Universitario Quiron Dexeus
Barcelona, Spain Recruiting -
Hospital Universitario Quiron Dexeus
Barcelona, Spain Not yet recruiting
Study contacts
- Study coordinator: Monica Parriego, PhD
- Email: monpar@dexeus.com
- Phone: 0034932274700
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.