Clinical trial Recruiting at 1 site Interventional Ages 18 to 50 Women only

Ultra-rapid blastocyst vitrification for donor oocyte cycles

Official title: Clinical Validation of Ultra-rapid Blastocyst Vitrification: a Randomized Pilot Study in Oocyte Donation Cycles

Run by Fundacion Dexeus · NCT07556601 · Data updated 2026-11-12

This pilot study tests whether ultra-rapid blastocyst vitrification is safe and feasible for donor oocytes compared with the standard method.

Quick facts

Study typeInterventional
Ages18 Years to 50 Years
SexWomen only
Enrollment80 (estimated)
SponsorFundacion Dexeus
Academic / other
Locations2 sites (Barcelona and 1 other locations)
StatusRecruiting
StartedJune 1, 2026
Main results expectedDecember 2027
Study endsMarch 2028
Registry record updatedJune 30, 2026
Trial IDNCT07556601 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Women receiving donor oocytes with blastocysts suitable for cryopreservation.

Probably not a fit

Cycles not reaching the blastocyst stage or those using PGT may not benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, interventional pilot study compares an ultra-rapid blastocyst vitrification protocol to the standard vitrification approach in recipients of donor oocytes. The main focus is on safety, feasibility, and preliminary clinical performance, including post-warming viability and potential impacts on clinical outcomes. The study builds on existing vitrification methods and investigates whether faster exposure to cryoprotectants and an additional embryological step affect outcomes. It is designed as an initial step before broader clinical use, to identify any safety concerns or practical workflow implications. The trial is conducted at a single leading center in Barcelona with two listed locations, under the lead sponsor Fundacion Dexeus.

Why it matters

Potential benefit: If successful, ultra-rapid vitrification could streamline laboratory workflow and potentially improve embryo survival and clinical outcomes after transfer.

How similar studies have gone: Clinical data on ultra-rapid blastocyst vitrification are limited, making this pilot study an exploratory step with uncertain similarity to prior work.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Recipients of donor oocytes
* Blastocysts suitable for cryopreservation

Exclusion Criteria:

* Cycles involving PGT
* Cycles not reaching blastocyst stage.

Where it's running

  • Hospital Universitario Quiron Dexeus
    Barcelona, Spain
    Recruiting
  • Hospital Universitario Quiron Dexeus
    Barcelona, Spain
    Not yet recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.