Two laparoscopic techniques for repairing inguinal hernias in children
Official title: Comparative Study of Laparoscopic Percutaneous Extraperitoneal Closure Versus Laparoscopic Intracorporeal Suture in Pediatric Hernia Repair.
Run by Quaid-e-Azam Medical College · NCT07915830 · Data updated 2026-11-12
This study tests whether LPEC or LIS works better for repairing inguinal hernias in children aged 1 to 15 who need laparoscopic repair.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 1 Year to 15 Years |
| Sex | All |
| Enrollment | 412 (estimated) |
| Sponsor | Quaid-e-Azam Medical College Academic / other |
| Locations | 1 site (Bahawalpur, Punjab Province) |
| Status | Recruiting |
| Started | May 12, 2026 |
| Main results expected | November 11, 2026 |
| Study ends | November 11, 2026 |
| Registry record updated | November 4, 2026 |
| Trial ID | NCT07915830 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children aged 1 to 15 years with unilateral or bilateral inguinal hernias planned for laparoscopic repair, without prior abdominal surgery or complex comorbidities specified.
✕Probably not a fit
Children with recurrent, incarcerated, or previously operated hernias, coagulopathy, undescended testes, major congenital anomalies, congenital heart disease, or cerebral palsy may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial compares two pediatric laparoscopic approaches for inguinal hernia repair: laparoscopic percutaneous extraperitoneal closure (LPEC) and laparoscopic intracorporeal suture (LIS). Participants are children with unilateral or bilateral hernias undergoing planned laparoscopic repair, excluding those with prior hernia operations, incarceration, or several major comorbidities. Randomization uses sealed opaque envelopes to assign participants to either LPEC or LIS. The study is conducted at Bahawal Victoria Hospital and led by Quaid-e-Azam Medical College. Outcomes will help determine if one technique offers superior safety or effectiveness in this population.
Why it matters
Potential benefit: If successful, the preferred technique could reduce recovery time, complications, or recurrence after pediatric hernia repair.
How similar studies have gone: Previous pediatric laparoscopic comparisons have shown varying outcomes, with some techniques performing similarly; this study adds contemporary randomized data for LPEC vs LIS.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * unilateral or bilateral inguinal hernia * planned to undergo laparoscopic hernia repair Exclusion Criteria: * recurrent hernia * hernia after previous abdominal surgery * incarcerated hernia * coagulopathy * Associated undescended testes * Major congenital abdominal anomalies * Children with congenital heart disease * Cerebral palsy.
Where it's running
-
Qauad-e-Azam Medical College
Bahawalpur, Punjab Province, Pakistan Recruiting
Study contacts
- Study coordinator: Fatima A Principal Investigator, MBBS
- Email: iffat.fatima47@gmail.com
- Phone: +92 321 6381440
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Shouldice groin hernia repair: permanent vs slowly dissolving stitches
We’re testing whether slowly dissolving stitches (PDS) work as well as permanent stitches (Prolene) for adults with a non-mesh Shouldice inguinal hernia repair.
-
Acupressure for Postoperative Pain After Laparoscopic TEP Hernia Repair
This trial tests whether true acupressure, given after surgery, reduces pain more than sham acupressure or standard care for adults undergoing laparoscopic TEP inguinal hernia repair.
-
TREPP: A Minimally Invasive Open Approach to Repair Inguinal Hernias
This study tests the trans rectus sheath extra-peritoneal procedure (TREPP) to repair inguinal hernias and see if it reduces pain and recurrence relative to traditional methods.
-
Camera-based non-contact vital sign monitoring during surgery
This project will try a camera-based non-contact system to measure heart rate, blood pressure, and oxygen levels in adults having surgery under general anesthesia.
-
Pneumoperitoneum time and bicarbonate changes during laparoscopic inguinal hernia repair
This study will see if longer pneumoperitoneum time during laparoscopic inguinal hernia repair causes changes in blood bicarbonate levels in adults.
-
Ultrasound-guided TAP and rectus sheath nerve blocks to improve recovery after open inguinal hernia repair.
This trial will test whether ultrasound-guided transversus abdominis plane (TAP) and/or rectus sheath (RS) nerve blocks reduce opioid use and speed recovery in adults having open unilateral inguinal hernia repair.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.