Clinical trial Recruiting at 1 site Interventional Ages 18 and up

TREPP: A Minimally Invasive Open Approach to Repair Inguinal Hernias

Official title: TransREctus Sheath PrePeritoneal Procedure (TREPP) for Inguinal Hernia Repair: A Single-center Prospective Study.

Run by Assiut University · NCT07618884 · Data updated 2026-11-12

This study tests the trans rectus sheath extra-peritoneal procedure (TREPP) to repair inguinal hernias and see if it reduces pain and recurrence relative to traditional methods.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment30 (estimated)
SponsorAssiut University
Academic / other
Locations1 site (Asyut, Asyut Governorate)
StatusRecruiting
StartedApril 15, 2025
Main results expectedJune 2026
Study endsSeptember 2026
Registry record updatedJune 1, 2026
Trial IDNCT07618884 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with a primary unilateral or bilateral inguinal hernia who are suitable for surgery and do not have strangulation or ASA IV-V comorbidities.

Probably not a fit

Patients with strangulated hernias or those with severe comorbidities may not benefit from TREPP and may require alternative approaches.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective cohort study evaluates TREPP, a minimally invasive open technique that uses the rectus sheath to access the preperitoneal space for inguinal hernia repair. The goal is to determine its safety, pain outcomes, and recurrence rates compared with standard repairs. Adults with either a primary unilateral or bilateral inguinal hernia are eligible, excluding those with strangulated hernias or severe comorbidities (ASA IV-V). Procedures are performed at Assiut University’s Faculty of Medicine in Egypt, led by Assiut University with no listed collaborators. Outcomes will help clarify whether TREPP offers advantages in pain, cosmetic results, and long-term recurrence.

Why it matters

Potential benefit: If successful, TREPP could reduce chronic postoperative inguinal pain and improve recovery after hernia repair.

How similar studies have gone: Previous reports suggest TREPP shows promise for effective repair with potential benefits in pain and recurrence, but broader validation is needed.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults with primary unilateral or bilateral inguinal hernia

Exclusion Criteria:

* Strangulated hernias.
* Severe comorbidities precluding surgery ((ASA Class IV,V)

Where it's running

  • Faculty of Medicine-Assiut University -Assiut-Egypt
    Asyut, Asyut Governorate, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.