TREPP: A Minimally Invasive Open Approach to Repair Inguinal Hernias
Official title: TransREctus Sheath PrePeritoneal Procedure (TREPP) for Inguinal Hernia Repair: A Single-center Prospective Study.
Run by Assiut University · NCT07618884 · Data updated 2026-11-12
This study tests the trans rectus sheath extra-peritoneal procedure (TREPP) to repair inguinal hernias and see if it reduces pain and recurrence relative to traditional methods.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Asyut, Asyut Governorate) |
| Status | Recruiting |
| Started | April 15, 2025 |
| Main results expected | June 2026 |
| Study ends | September 2026 |
| Registry record updated | June 1, 2026 |
| Trial ID | NCT07618884 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with a primary unilateral or bilateral inguinal hernia who are suitable for surgery and do not have strangulation or ASA IV-V comorbidities.
✕Probably not a fit
Patients with strangulated hernias or those with severe comorbidities may not benefit from TREPP and may require alternative approaches.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective cohort study evaluates TREPP, a minimally invasive open technique that uses the rectus sheath to access the preperitoneal space for inguinal hernia repair. The goal is to determine its safety, pain outcomes, and recurrence rates compared with standard repairs. Adults with either a primary unilateral or bilateral inguinal hernia are eligible, excluding those with strangulated hernias or severe comorbidities (ASA IV-V). Procedures are performed at Assiut University’s Faculty of Medicine in Egypt, led by Assiut University with no listed collaborators. Outcomes will help clarify whether TREPP offers advantages in pain, cosmetic results, and long-term recurrence.
Why it matters
Potential benefit: If successful, TREPP could reduce chronic postoperative inguinal pain and improve recovery after hernia repair.
How similar studies have gone: Previous reports suggest TREPP shows promise for effective repair with potential benefits in pain and recurrence, but broader validation is needed.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults with primary unilateral or bilateral inguinal hernia Exclusion Criteria: * Strangulated hernias. * Severe comorbidities precluding surgery ((ASA Class IV,V)
Where it's running
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Faculty of Medicine-Assiut University -Assiut-Egypt
Asyut, Asyut Governorate, Egypt Recruiting
Study contacts
- Study coordinator: Mohamad Raafat, MD
- Email: mohamad_raafat10@yahoo.com
- Phone: 0201067877622
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.