Clinical trial Recruiting at 1 site Interventional Ages 18 to 50

Transseptal Suture vs Anterior Nasal Packing After Septoplasty

Official title: Trans Septal Suture Technique Verses Anterior Nasal Packing After Septoplasty - A Comparative Study

Run by Pakistan Institute of Medical Sciences · NCT07745127 · Data updated 2026-11-12

This study tests whether using a trans-septal suture or anterior nasal packing after septoplasty better reduces postoperative nasal pain and bleeding in adults with a deviated septum.

More Deviated Nasal Septum trials

Quick facts

Study typeInterventional
Ages18 Years to 50 Years
SexAll
Enrollment60 (estimated)
SponsorPakistan Institute of Medical Sciences
Government
Locations1 site (Islamabad, Fedral)
StatusRecruiting
StartedMay 14, 2026
Main results expectedNovember 12, 2026
Study endsNovember 12, 2026
Registry record updatedAugust 4, 2026
Trial IDNCT07745127 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–50 with symptomatic deviated nasal septum undergoing septoplasty, with no prior nasal surgery or listed exclusion conditions.

Probably not a fit

Patients with previous nasal surgery, chronic sinus disease, pregnancy, immunocompromise, significant systemic disease, or recent steroid/anticoagulant therapy may not see a benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized comparison examines two techniques used after septoplasty to manage postoperative pain and bleeding in patients aged 18 to 50 with a deviated nasal septum. Participants who are already admitted will be evaluated on the first postoperative day to compare outcomes between the trans-septal suture and anterior nasal packing methods. The study is conducted at Pakistan Institute of Medical Sciences in Islamabad, with Ghazal Iftakhar as lead sponsor. Primary outcomes focus on postoperative nasal pain and bleeding, with eligibility limited to adults without prior nasal surgery or confounding conditions such as chronic rhinosinusitis, pregnancy, immunocompromise, or recent steroid/anticoagulant use. This is an interventional trial without a specified phase, comparing two standard post-septoplasty approaches.

Why it matters

Potential benefit: If successful, the preferred post-septoplasty technique could reduce pain and bleeding, improving recovery.

How similar studies have gone: Evidence from similar postoperative techniques has shown variable effects on pain and bleeding; this study tests direct comparison in this context.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* symptomatic deviated nasal septum
* 18-50 years of age
* both male and female genders

Exclusion Criteria:

* history of previous nasal surgery
* presence of chronic rhinosinusitis with or without nasal polyposis
* pregnant females
* immunocompromised patients
* patients with pulmonary and/or cardiovascular disorders
* patients those who received steroidal or anticoagulant therapy within last 30 days.

Where it's running

  • Pakistan Institute of Medical Sciences (PIMS), Islamabad.
    Islamabad, Fedral, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.