Using numerical modeling to diagnose respiratory disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to objectively measure chronic nasal obstruction (CNO) using computational fluid dynamics simulations to analyze airflow in the nasal cavities. By collecting retrospective clinical and scannographic data, the study seeks to identify specific airflow parameters that correlate with respiratory comfort in both healthy individuals and patients with CNO. The goal is to improve diagnostic accuracy and reduce unnecessary surgeries by providing a reliable measurement of nasal obstruction. The study focuses on patients with nasal obstruction due to septal deviation and other morphological issues.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years ≤ age \< 70 years
* BMI \< 30 kg/m2
* Subject or Patient of Caucasian ethnic origin or from the Mediterranean region.
* Asymptomatic subject with or without a septal deviation without sinonasal disease with a NOSE score ≤ 7 Or Patient suffering from chronic nasal obstruction of morphological origin (symptomatic septal or nasoseptal deviation) requiring surgical management with a NOSE score ≥ 9/20, without or .with sleep apnea with an Apnea-hypopnea index ≤ 20 with no other cause than this apnea syndrome

Exclusion Criteria:

* Acute or chronic rhinosinusitis with or without polyps (except controlled allergic rhinitis)
* Vasculitis
* Empty nasal cavity syndrome
* Septal perforations
* History of nasal plastic surgery, sinonasal endoscopic surgery and cancer with head or neck radiotherapy
* Uncontrolled bronchopulmonary pathology
* Treatments with nasal vasomotor repercussions.

Where it's running

• CHU de Bordeaux
  Bordeaux, France Recruiting

Study contacts

• Study coordinator: Ludovic De GABORY, Pr
• Email: ludovic.de-gabory@chu-bordeaux.fr
• Phone: 05 56 79 87 88

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.