Transforming powder dressing versus standard dressing for acute partial-thickness burns

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, controlled post-marketing trial enrolls adults 18–65 hospitalized with an acute partial-thickness burn involving under 20% total body surface area. Participants are randomized 1:1 to receive either the Altrazeal transforming powder dressing or a typical standard-of-care burn dressing, with wound cleaning and debridement per usual burn care. Wounds are photographed, measured, and monitored for healing and pain across up to eight visits during hospitalization and up to 28 days after enrollment. A patient satisfaction survey about the dressing is completed when the wound heals or at the end of follow-up.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Hospitalized patients who are receiving burn care; patients may be discharged when clinically stable and continue with outpatient treatment.
* Men and women (women cannot be pregnant or breast feeding) ages 18-65 years old
* Wounds must be partial thickness, involving up to 20% of the total body surface area.
* Burn injury should be less than 72 hours old
* Willing and able to comply with protocol mandated scheduled study visits/clinical evaluations.
* Willing and able to provide written informed consent.

Exclusion Criteria:

* Known allergy to TPD or its components

  * Women who are pregnant, breast feeding, or plan to get pregnant during the study period.
* Infected wounds
* Presence of any full thickness (third degree) burns
* Electrical burns
* Heavily draining burns due to underlying chronic lymphedema or other conditions
* Concurrent clinical condition within the judgement of the clinician, pose a health risk to the patient, delay wound healing, or otherwise influence the outcome of the study.
* History of poor wound healing and/or skin/immune system condition

  * Deemed by clinician not to be suitable
* Unwilling or not able to provide consent or comply with protocol or required visits
* Developmental disability/significant psychological disorder which can impair the subjects ability to provide informed consent, or participate in the study protocol
* Active alcohol or substance abuse

Where it's running

• University of California-Irvine
  Orange, California, United States Recruiting
• MedStar Washington Hospital Center
  Washington D.C., District of Columbia, United States Recruiting
• Jackson Memorial Hospital UM/JMH Burn Center
  Miami, Florida, United States Recruiting
• University of Louisville Health
  Louisville, Kentucky, United States Recruiting
• Westchester Medical Center
  Valhalla, New York, United States Recruiting
• University of Texas SW (Parkland)
  Dallas, Texas, United States Recruiting

Study contacts

• Principal investigator: Jonathan Saxe, MD — ULURU Inc.
• Study coordinator: Vai Shah
• Email: vshah@uluruinc.com
• Phone: 2149055145

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Predictors of In-Hospital Death in Severe Abdominal Injury

  This study will follow adults with severe abdominal trauma at a large Egyptian hospital to see which factors best predict in-hospital death.

  Recruiting Minia University · Minya, Minya Governorate · NCT07843628

• Humidification methods in trauma ICU patients on mechanical ventilation

  This study tests whether active heated humidifiers or passive heat-and-moisture exchangers work better in trauma ICU patients who need long-term mechanical ventilation.

  Recruiting Assiut University · Asyut, Asyut Governorate · NCT07713238

• Food Is Medicine post-operative meal delivery for orthopaedic trauma patients

  This project will try whether delivering medically tailored meals and shakes for 12 days after surgery helps orthopaedic trauma patients recover better and improve metabolic lab markers.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT07169448

• WounDx device to help guide delayed closure of large traumatic limb wounds

  This pilot tests whether the WounDx device can help surgeons decide when delayed closure will successfully heal large traumatic extremity wounds in adults.

  Recruiting at 5 sites Henry M. Jackson Foundation for the Advancement of Military Medicine · Birmingham, Alabama and 4 other locations · NCT06921707

• Acupuncture for relieving symptoms of Gulf War Illness

  This trial will test whether regular acupuncture can help veterans with Gulf War Illness feel less fatigued, have less pain, and improve physical functioning.

  Recruiting at 3 sites University of Utah · Berkeley, California and 9 other locations · NCT06716411

• 4-Aminopyridine to help heal second-degree skin burns

  This trial will try 4-aminopyridine in adults with recent second-degree burns to see if it speeds healing.

  Recruiting Phase 2 University of Arizona · Tucson, Arizona · NCT06596434

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.