Transaxillary robotic thyroidectomy with modified radical neck dissection versus conventional open surgery for papillary thyroid cancer with lateral lymph node spread

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This comparative interventional study enrolls adults with papillary thyroid carcinoma and ipsilateral lateral cervical lymph node metastasis to receive either a transaxillary robotic thyroidectomy with modified radical neck dissection or conventional open surgery. Eligible patients are 18–70 years old with tumors under 3.0 cm and no extrathyroidal extension by imaging, and surgeons will follow standardized operative and perioperative protocols. Outcomes will include oncologic measures (lymph node clearance, recurrence), surgical complications, cosmetic outcomes, and postoperative quality of life, tracked during inpatient recovery and scheduled follow-up visits. All procedures are performed at Sun Yat-sen Memorial Hospital with long-term follow-up to compare safety and effectiveness between approaches.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18-70 years old, male or female;
* papillary thyroid carcinoma with ipsilateral lateral cervical lymph node metastasis confirmed by FNAB;
* thyroid tumor of less than 3.0 cm in the largest diameter;
* lack of extrathyroidal extensions as estimated by preoperative ultrasonography and CT.

Exclusion Criteria:

* level I or contralateral neck node metastases.
* enlarged lymph node of larger than 2.0 cm in the short diameter.
* suspected perinodal infiltration of metastatic lymph nodes.
* cervical or/and thoracic deformity.
* life-threatening diseases of liver, kidney, heart and other organs, or abnormal coagulation function.
* clinical evidence of distant metastases such as in the lung, bone, and so on.
* history of previous neck surgery and/or radiation therapy.
* intolerable to general anesthesia
* refuse either surgical procedure
* unwilling to cooperate with long-term follow-up evaluation.

Where it's running

• Sun Yat-sen Memorial Hospital
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Study coordinator: Lin
• Email: linpliang3@mail.sysu.edu.cn
• Phone: 0086-020-34071439

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Using indocyanine green to find sentinel lymph nodes during mastectomy

  This pilot will test whether injecting indocyanine green and using fluorescence during mastectomy can find sentinel lymph nodes in women with clinically node-negative invasive breast cancer.

  Recruiting at 2 sites St. Antonius Hospital · Zwolle, Overijssel and 1 other locations · NCT07362485

• WeChat-based human-centered nursing support for people undergoing awake thermal ablation for papillary thyroid carcinoma

  This study tests whether WeChat-based human-centered nursing support helps people with papillary thyroid carcinoma feel less anxious and have better quality of life during and after awake thermal ablation.

  Recruiting China-Japan Friendship Hospital · Beijing · NCT07302672

• Using indocyanine green to identify sentinel lymph nodes during breast cancer surgery

  This project tests whether indocyanine green dye and a fluorescence camera can be used instead of the radioactive tracer to find sentinel lymph nodes in adults having breast cancer surgery who are clinically node-negative.

  Recruiting at 7 sites St. Antonius Hospital · Alkmaar and 6 other locations · NCT07146295

• AI-based diagnostic model for detecting lymphatic metastasis in cancer

  This study is testing a new AI tool to see if it can better detect cancer spread to lymph nodes compared to the usual methods used by doctors.

  Recruiting Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT06517979

• Factors affecting recurrence after thermal ablation of papillary thyroid carcinoma

  This study looks at patients with papillary thyroid cancer who have had thermal ablation to see what factors might affect whether their cancer comes back.

  Recruiting Beijing Friendship Hospital · Beijing · NCT05962892

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.