Factors affecting recurrence after thermal ablation of papillary thyroid carcinoma
Official title: A Study of Factors Influencing Recurrence After Thermal Ablation of Papillary Thyroid Carcinoma
Run by Beijing Friendship Hospital · NCT05962892 · Data updated 2026-11-12
This study looks at patients with papillary thyroid cancer who have had thermal ablation to see what factors might affect whether their cancer comes back.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | Beijing Friendship Hospital Academic / other |
| Locations | 1 site (Beijing) |
| Status | Recruiting |
| Started | February 1, 2024 |
| Main results expected | February 28, 2028 |
| Study ends | February 28, 2028 |
| Registry record updated | January 30, 2024 |
| Trial ID | NCT05962892 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older with single malignant nodules of papillary thyroid carcinoma that meet specific ultrasound criteria.
✕Probably not a fit
Patients with multiple malignant tumors, those who cannot tolerate surgery, or those with cognitive impairments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study establishes a prospective cohort of patients with papillary thyroid carcinoma (PTC) who have undergone thermal ablation since February 2023. It collects preoperative and postoperative demographic data, ultrasonography results, laboratory tests, and thyroid disease-related scales such as fatigue, depression, and stress. The study aims to analyze the factors influencing the recurrence of PTC in these patients.
Why it matters
Potential benefit: If successful, this study could help identify key factors that influence the recurrence of papillary thyroid carcinoma, leading to improved patient management and outcomes.
How similar studies have gone: While there may be studies on thyroid cancer recurrence, this specific observational approach focusing on thermal ablation is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: ①≥18 years old; ② Obtain informed consent; ③ Ultrasonography showed that malignant nodules were single, the maximum diameter of nodules was ≤1cm and the distance from the capsule was ≥2mm. ④ no lymph node metastasis or other extra-glandular metastasis in the neck; ⑤ PTC was confirmed by fine needle puncture pathology; ⑥ Patients who do not meet Article 3, who still strongly request thermal ablation while fully informing the patient of the risk of recurrence, and who have been clinically assessed to be technically capable of thermal ablation Exclusion Criteria:① Pregnant or lactating patients; ② Patients with other malignant tumors and not suitable for ablation by clinical evaluation; ③ Patients who cannot tolerate surgery; ④ Patients with cognitive impairment and other conditions who cannot accurately fill in thyroid-related questionnaires.
Where it's running
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Beijing Friendship Hospital
Beijing, China Recruiting
Study contacts
- Study coordinator: Xianquan Shi, PhD
- Email: sonoshixq@ccmu.edu.cn
- Phone: 18510085125
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.