Trans-spinal Electromagnetic Neuromodulation added to physical therapy for discogenic L5-S1 radiculopathy
Official title: Effect of Trans-spinal Electromagnetic Neuromodulation on Pain, Functional Outcome and Motor Evoked Potential in Patients With Discogenic Lumbosacral Radiculopathy
Run by Cairo University · NCT07743424 · Data updated 2026-11-12
This study tests whether adding trans-spinal electromagnetic neuromodulation to standard physical therapy helps people with unilateral disc-related lower back nerve pain.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 40 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Giza) |
| Status | Recruiting |
| Started | September 10, 2026 |
| Main results expected | September 10, 2026 |
| Study ends | February 10, 2027 |
| Registry record updated | September 11, 2026 |
| Trial ID | NCT07743424 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults 20–40 with unilateral chronic discogenic lumbosacral radiculopathy confirmed by MRI and meeting the specified neurophysiological criteria, without prior lumbar surgeries or other major spine conditions.
✕Probably not a fit
Patients with bilateral symptoms, spine stenosis, prior spine surgeries, or other excluded conditions may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults aged 20–40 with unilateral chronic discogenic lumbosacral radiculopathy will be randomized to receive either trans-spinal electromagnetic neuromodulation plus conventional physical therapy or conventional physical therapy alone for six weeks. Outcomes are measured at the start and after the six-week treatment period. The trial focuses on patients with MRI-confirmed unilateral disc herniation and specific neurophysiological criteria. The study is conducted at an outpatient clinic in Cairo and is led by a named sponsor with no listed collaborators.
Why it matters
Potential benefit: If successful, the approach could improve pain and function for patients with discogenic radiculopathy beyond standard physical therapy alone.
How similar studies have gone: Previous work in neuromodulation approaches for radiculopathy has shown promise, but this specific trans-spinal method with six weeks of therapy is being evaluated.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. patient age range from 20 -40 from both sexes. 2. Unilateral chronic lumbosacral radiculopathy confirmed by neurosurgeon for more than 3 months. 3. Unilateral paracentral or lateral intervertebral disc herniation confirmed by MRI . 4. one of the following: 1. H- reflex amplitude side to side difference 67% in absence of latency difference. 2. H- reflex amplitude side to side difference smaller than 50% in presence of latency difference. c - Side to side H- reflex latency difference more than 1 msec. d- Prolonged H-reflex latency more than 30 msec. Exclusion Criteria: 1. Hypertension 2. Diabetes. 3. Lumbar canal stenosis 4. Pervious surgeries 5. Scoliosis 6. Kyphosis 7. Spinal fracture 8. Bilateral symptoms.
Where it's running
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Outpatient Clinic at the Faculty of Physical Therapy Cairo
Giza, Egypt Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.