Training to improve cognitive strategies for people with psychotic disorders
E-SMART: Examining Strategy Monitoring and Remediation Training for Schizophrenia
NA · University of Toronto · NCT04756388
This study tests different training methods to see which one helps people with schizophrenia-spectrum disorders improve their thinking skills the most.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | University of Toronto (other) |
| Locations | 1 site (Toronto, Ontario) |
| Trial ID | NCT04756388 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of Executive Function Training, which focuses on enhancing executive functioning in individuals with schizophrenia-spectrum disorders. Participants will be divided into three groups: one receiving full executive function training, another undergoing only computerized cognitive training, and a third focusing solely on strategy development. Each group will participate in virtual sessions over four weeks, with additional practice at home. The aim is to determine which approach best supports cognitive improvement.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-65 with a clinical diagnosis of schizophrenia or related psychotic disorders who are comfortable using a computer.
Not a fit: Patients with recent cognitive training experience or those with neurological conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved cognitive functioning and daily living skills for patients with psychotic disorders.
How similar studies have performed: Previous studies have shown promise in cognitive remediation approaches for psychotic disorders, suggesting potential for success in this study.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * clinical diagnosis of schizophrenia, schizoaffective disorder or any other psychotic disorder (based on DSM-V) * 18-65 years of age * know how to use a computer * not abusing drugs or alcohol * can read and speak English. Exclusion Criteria: * enrolled in a cognitive training program in the last 6 months * neurological disease or neurological damage * medical illnesses that can change neurocognitive function * medical history of head injury with loss of consciousness * physical handicaps
Where this trial is running
Toronto, Ontario
- University of Toronto Scarborough — Toronto, Ontario, Canada (RECRUITING)
Study contacts
- Principal investigator: Michael Best, PhD — University of Toronto
- Study coordinator: Michael Best, PhD
- Email: m.best@utoronto.ca
- Phone: 416-208-4825
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Psychotic Disorders, Executive Dysfunction, psychosis, schizophrenia, cognitive remediation, executive functioning, strategy monitoring, computerized practice