Training to help individuals with neglect after stroke

Examining Metacognitive Strategy Training for Individuals With Unilateral Spatial Neglect

Not applicable Interventional University of Pittsburgh · NCT06400147

This study is testing a new training program to help people who have had a stroke and struggle with paying attention to one side of their body or surroundings, to see if it can improve their awareness and daily functioning.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment38 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Pittsburgh Academic / other
Locations1 site (Pittsburgh, Pennsylvania)
Trial IDNCT06400147 on ClinicalTrials.gov

What this trial studies

This study focuses on individuals who have experienced a stroke and suffer from unilateral spatial neglect, a condition that impairs their ability to pay attention to one side of their body or environment. It aims to evaluate the effectiveness of metacognitive strategy training, which teaches participants to set personal goals, self-assess their daily activities, and develop strategies to improve their performance. The study will measure the impact of this training on self-awareness, disability, and the severity of neglect symptoms. By tailoring the intervention specifically for individuals with neglect, the study seeks to provide new insights into effective treatment options for this population.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who have had a stroke and exhibit signs of unilateral neglect.

Not a fit: Patients with severe global aphasia, dementia, or active major psychiatric disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce disability and improve daily functioning for stroke survivors with neglect.

How similar studies have performed: While strategy training shows promise, this specific approach tailored for individuals with neglect has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* primary diagnosis of stroke
* admission to inpatient rehabilitation facility
* ≥18 years old
* presence of neglect as determined by score of \<18 on the Virtual Reality Lateralized Attention Test (VRLAT) or score below established cutoff for neglect on one of the six subtests of the Behavioral Inattention Test (BIT)

Exclusion Criteria:

* Boston Diagnostic Aphasia Examination (BDAE) Severity Scale score of 0 (severe global aphasia)
* diagnosis of dementia indicated in medical record
* diagnosis of active major depressive disorder/bipolar/psychotic disorder indicated in medical record
* anticipated length of stay \<10 days

Where this trial is running

Pittsburgh, Pennsylvania

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions StrokeNeglect, Hemispatial
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.