Training to help individuals with neglect after stroke
Official title: Examining Metacognitive Strategy Training for Individuals With Unilateral Spatial Neglect
Run by University of Pittsburgh · NCT06400147 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing a new training program to help people who have had a stroke and struggle with paying attention to one side of their body or surroundings, to see if it can improve their awareness and daily functioning.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 38 (estimated) |
| Sponsor | University of Pittsburgh Academic / other |
| Locations | 1 site (Pittsburgh, Pennsylvania) |
| Trial ID | NCT06400147 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older who have had a stroke and exhibit signs of unilateral neglect.
✕Probably not a fit
Patients with severe global aphasia, dementia, or active major psychiatric disorders may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on individuals who have experienced a stroke and suffer from unilateral spatial neglect, a condition that impairs their ability to pay attention to one side of their body or environment. It aims to evaluate the effectiveness of metacognitive strategy training, which teaches participants to set personal goals, self-assess their daily activities, and develop strategies to improve their performance. The study will measure the impact of this training on self-awareness, disability, and the severity of neglect symptoms. By tailoring the intervention specifically for individuals with neglect, the study seeks to provide new insights into effective treatment options for this population.
Why it matters
Potential benefit: If successful, this intervention could significantly reduce disability and improve daily functioning for stroke survivors with neglect.
How similar studies have gone: While strategy training shows promise, this specific approach tailored for individuals with neglect has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * primary diagnosis of stroke * admission to inpatient rehabilitation facility * ≥18 years old * presence of neglect as determined by score of \<18 on the Virtual Reality Lateralized Attention Test (VRLAT) or score below established cutoff for neglect on one of the six subtests of the Behavioral Inattention Test (BIT) Exclusion Criteria: * Boston Diagnostic Aphasia Examination (BDAE) Severity Scale score of 0 (severe global aphasia) * diagnosis of dementia indicated in medical record * diagnosis of active major depressive disorder/bipolar/psychotic disorder indicated in medical record * anticipated length of stay \<10 days
Where it's running
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University of Pittsburgh
Pittsburgh, Pennsylvania, United States Recruiting
Study contacts
- Principal investigator: Emily Grattan, PhD — University of Pittsburgh
- Study coordinator: Emily Grattan, PhD
- Email: esg39@pitt.edu
- Phone: 412-648-0619
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Strategy training to improve attention for people with spatial neglect after stroke
This program tests whether metacognitive strategy training helps people with spatial neglect after stroke pay more attention and carry out daily activities more independently.
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AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals
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Web-based therapy using action observation and mirror therapy for arm weakness after stroke
This trial tests whether a mobile telerehabilitation app delivering action observation therapy (AOT) alone or combined AOT with mirror therapy (AOT-MT) can improve upper limb function in people with subacute stroke.
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Remote Ischaemic Conditioning for Fatigue After Stroke 2
Aat least 12 weeks after stroke, adults with post-stroke fatigue will try a simple hand-arm cuff treatment at home to see if it helps reduce fatigue.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.