Tracking long-term health and family effects after intensive care in the DACH region
Official title: Post-Intensive Care Syndrome - Multicentre Prospective Registry Database of the DACH Region
Run by Medical University of Vienna · NCT07290712 · Data updated 2026-11-12
This project will try to follow adults who spent more than 72 hours in the ICU and their families to see which factors lead to lasting physical, cognitive, or mental health problems.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | Medical University of Vienna Academic / other |
| Locations | 4 sites (Vienna, State of Vienna and 3 other locations) |
| Status | Recruiting |
| Started | February 4, 2026 |
| Main results expected | November 1, 2030 |
| Study ends | November 1, 2035 |
| Registry record updated | August 25, 2026 |
| Trial ID | NCT07290712 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults who had an ICU stay longer than 72 hours (with capacity for consent or appropriate proxy consent) and their close relatives are the intended participants.
✕Probably not a fit
People under 18, patients receiving end-of-life care at screening, and those with very short ICU stays are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective multicentre registry that collects clinical data during ICU stays and follows patients and their relatives for up to five years using standardized questionnaires and blood samples. The protocol is organized into six modules covering ICU data, staged post-ICU follow-ups, environmental and psychiatric factors, translational biological sampling, and family-system effects. The primary focus is on improving diagnostic and therapeutic strategies, while secondary aims include identifying risk factors, measuring impairment severity, and exploring underlying biological mechanisms. Recruitment occurs at several major academic centers in the DACH region with both in-person and remote follow-up elements.
Why it matters
Potential benefit: If successful, the registry could help clinicians identify patients and families at high risk for PICS and target follow-up or interventions to reduce long-term disability.
How similar studies have gone: Previous observational cohorts and registries have documented high rates of PICS and some risk factors, but large multicentre registries combining clinical, family, and biological data are still relatively uncommon.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with an ICU stay longer than 72 hours will be included Exclusion Criteria: * Age \< 18 years old * Patients who receive end-of-life care at the time of screening
Where it's running
-
Medical University of Vienna
Vienna, State of Vienna, Austria Recruiting -
Universitätsklinikum Augsburg
Augsburg, Bavaria, Germany Recruiting -
Charité - Universitätsmedizin Berlin
Berlin, State of Berlin, Germany Recruiting -
Universitätsklinikum Würzburg
Würzburg, Bavaria, Germany Not yet recruiting
Study contacts
- Principal investigator: Stefan J Schaller, MD — Medical University of Vieanna
- Study coordinator: PICS-DACH Steering Committee
- Email: pics-dach-sc@listserv.muv.ac.at
- Phone: +4314040041020
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.