Text reminders and mindfulness messages to support people taking opioid medications
Official title: Integrating Mindfulness and mHealth Approaches for Treating Opioid Use Disorder
Run by University of New Mexico · NCT07350148 · Data updated 2026-11-12
This project will test whether daily medication reminder texts plus up to six mindfulness messages per day help people taking medications for opioid use disorder stick to their medication and manage cravings, pain, and withdrawal.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | University of New Mexico Academic / other |
| Locations | 1 site (Albuquerque, New Mexico) |
| Status | Recruiting |
| Started | October 13, 2025 |
| Main results expected | March 2027 |
| Study ends | March 2029 |
| Registry record updated | January 20, 2026 |
| Trial ID | NCT07350148 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) within six months of starting or restarting daily methadone or buprenorphine who have a cellphone that receives texts, internet access for surveys, and can provide informed consent are ideal candidates.
✕Probably not a fit
People not taking daily medications for opioid use disorder, those without a cellphone or internet access, or those needing more intensive in-person care are unlikely to benefit from this text-message intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-site, interventional trial enrolls 60 adults who recently started or restarted daily methadone or buprenorphine and delivers daily medication reminder texts for at least 24 weeks and up to six mindfulness texts per day for a four-week period. The study uses a micro-randomized design so participants are randomized each day to receive a varying number (0–6) of mindfulness messages, with twice-daily self-report questions collected during the mindfulness period. Primary outcomes include self-reported medication adherence and changes in craving, pain/pain interference, and withdrawal symptoms; secondary measures include message engagement, state mindfulness, values-based living, substance misuse, and self-efficacy. Data are collected at baseline and at months 1, 2, and 6 to track short- and longer-term effects.
Why it matters
Potential benefit: If successful, the approach could increase medication adherence and reduce craving, pain, or withdrawal symptoms using low-cost, scalable text messaging.
How similar studies have gone: Prior mobile health and text-message interventions have shown modest improvements in medication adherence and symptoms in substance use and other chronic conditions, but using a daily micro-randomized mindfulness texting approach for MOUD is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years of age or older * Have a cellphone that can receive text messages * Have internet access to complete study surveys * Willing to comply with all study procedures and be available for the duration of the study * Within 6 months of starting or resuming to take daily methadone or buprenorphine (or suboxone/subutex) * Able to understand study requirements and provide informed consent Exclusion Criteria: * None
Where it's running
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University of New Mexico
Albuquerque, New Mexico, United States Recruiting
Study contacts
- Study coordinator: Frank Schwebel, PhD
- Email: fschwebel@unm.edu
- Phone: 505-456-3014
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.