3D MRI Elastography to Peek at Vestibular Schwannoma Stiffness and How It Relates to Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, single-center study evaluates the feasibility and clinical value of three-dimensional magnetic resonance elastography (3D MRE) for preoperative assessment of vestibular schwannomas. Researchers will compare MRE-derived stiffness and adhesion maps with intraoperative observations and tumor histology, and will follow facial nerve function postoperatively to see if MRE findings relate to prognosis. Approximately 30 patients undergoing planned surgical resection will be enrolled. The goal is to determine if MRE can serve as a noninvasive biomarker to aid risk stratification, surgical planning, and patient counseling. Interventions are observational in nature, focusing on imaging correlations rather than treatment modification.

Why it matters

Who can join: the full rules

Inclusion Criteria:

-All patients undergoing vestibular schwannoma resection surgery are eligible for inclusion in the study cohort.

Exclusion Criteria:

* Patients with metallic implants or foreign bodies in their bodies (pacemakers, artificial metallic heart valves, metal joints, metal implants, and those who can not remove dentures, insulin pumps, or contraceptive rings)
* Pregnant women in the first trimester (within three months)
* Patients with severe claustrophobia or anxiety
* Patients with severe fever
* Patients who can not tolerate MRE
* Patients with vascular malformations and aneurysms.
* Patients who do not sign an informed consent

Where it's running

• Shengjing hospital
  Shenyang, Liaoning, China Recruiting

Study contacts

• Principal investigator: Anhua Wu, MD — Shengjing Hospital
• Study coordinator: wen Cheng, MD
• Email: cmu071207@163.com
• Phone: 18940250139

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.