Aerosol box use during cardiopulmonary arrest
Official title: Impact of Aerosol Box Use During Cardiopulmonary Arrest: A Multicenter Study
Run by KidSIM Simulation Program · NCT05868239 · Data updated 2026-11-12
This project tests whether using an aerosol box during emergency airway procedures and chest compressions lowers particle spread and is practical for healthcare teams treating cardiac arrest patients, including those with COVID-19.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 240 (estimated) |
| Sponsor | KidSIM Simulation Program Research network |
| Locations | 4 sites (Los Angeles, California and 3 other locations) |
| Status | Recruiting |
| Started | September 1, 2023 |
| Main results expected | September 1, 2025 |
| Study ends | December 1, 2026 |
| Registry record updated | September 5, 2025 |
| Trial ID | NCT05868239 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are healthcare providers who perform airway management or CPR (attendings, fellows, residents, nurses, respiratory therapists, physician assistants, or health care aides) with Basic or Advanced Life Support certification.
✕Probably not a fit
Patients who do not require aerosol‑generating procedures or those who need immediate airway access where a barrier would delay care are unlikely to benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This multicenter interventional study uses simulated resuscitations to compare aerosol dispersion and clinical performance with and without an aerosol box during bag‑valve‑mask ventilation, endotracheal intubation, and chest compressions. Trained airway and CPR providers at tertiary pediatric and adult centers perform standardized scenarios while researchers measure particle spread, timing, and procedural errors. The protocol includes typical clinical roles (airway provider and CPR provider) and records ergonomics and team workflow impacts. Results will inform whether the device meaningfully reduces airborne exposure without compromising resuscitation performance.
Why it matters
Potential benefit: If successful, this work could reduce healthcare worker exposure to infectious aerosols during resuscitation and guide safer device use or design.
How similar studies have gone: Prior small simulation and observational studies suggest aerosol boxes can reduce visible aerosol spread but have mixed evidence because they may impede procedural speed and ergonomics.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Airway Provider: * Attending physician, fellow or resident in adult or pediatric emergency medicine, pediatric intensive care, general pediatrics or pediatric/adult anesthesia * Adult or Pediatric Advanced Life Support certification. CPR Provider: * Attending physician, resident, fellow, nurse, respiratory therapist, physician assistant or health care aide * Basic Life Support, Adult or Pediatric Advanced Life Support certification Exclusion Criteria: * Decline to provide informed consent * Unable to perform tasks required of the role due to physical limitations.
Where it's running
-
Department of Emergency Medicine, Children's Hospital of Los Angeles
Los Angeles, California, United States Recruiting -
KidSIM, Alberta Children's Hospital
Calgary, Alberta, Canada Recruiting -
Department of Pediatrics, The Hospital for Sick Children
Toronto, Ontario, Canada Recruiting -
Department of Pediatrics, CHU Sainte-Justine
Montreal, Quebec, Canada Completed
Study contacts
- Principal investigator: Adam C Cheng, MD — University of Calgary
- Study coordinator: Adam Cheng, MD
- Email: adam.cheng@albertahealthservices.ca
- Phone: (403)955-2633
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.