TCAF versus MTUN with soft tissue grafts for a single gum recession in the lower premolar area
Official title: An RCT Comparing Tunneled Coronally Advanced Flap (TCAF) and Modified Tunnel Technique (MTUN) in Combination With a Soft Tissue Graft for Single Recession Coverage
Run by University Hospital, Ghent · NCT07158541 · Data updated 2026-11-12
This compares whether a tunneled coronally advanced flap (TCAF) or a modified tunnel (MTUN), each combined with a connective tissue graft, gives better root coverage for adults with a single gum recession in the lower premolar area.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 24 (estimated) |
| Sponsor | University Hospital, Ghent Academic / other |
| Locations | 1 site (Ghent, Oost-Vlaanderen) |
| Status | Recruiting |
| Started | August 25, 2025 |
| Main results expected | December 31, 2037 |
| Study ends | December 31, 2037 |
| Registry record updated | September 16, 2025 |
| Trial ID | NCT07158541 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older in good general health with good oral hygiene and a single gingival recession in the premandible who are non-smokers and not pregnant are ideal candidates.
✕Probably not a fit
Smokers, pregnant women, people with multiple or widespread recessions, or those with poor oral hygiene or significant systemic disease are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial enrolls adults with a single gingival recession in the premandible and good oral hygiene to compare two surgical techniques: tunneled coronally advanced flap (TCAF) and modified tunnel (MTUN), both paired with a connective tissue graft. Participants are randomly assigned to the test (TCAF) or control (MTUN) group and followed for short- and long-term measures of root coverage. Primary outcomes are average root coverage at specified follow-up times, with secondary outcomes including sensitivity, aesthetics, and tissue thickness. Smokers and pregnant women are excluded, and procedures are performed at the Department of Periodontology and Implantology of Ghent University.
Why it matters
Potential benefit: If one technique provides better root coverage, patients could experience less tooth sensitivity, improved appearance, and easier oral hygiene for the treated tooth.
How similar studies have gone: Both tunnel and coronally advanced flap techniques combined with connective tissue grafts have shown good root coverage in prior reports, but randomized head-to-head comparisons of TCAF versus MTUN are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * at least 18 years old * good oral hygiene * presence of one recession in the premandible * good general health Exclusion Criteria: * smoker * pregnant women (assessed at each visit; if the patient appears pregnant during follow-up, x-rays will not be taken)
Where it's running
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Department of Periodontology and Implantology of Ghent University
Ghent, Oost-Vlaanderen, Belgium Recruiting
Study contacts
- Study coordinator: Véronique Prof. Dr. Christiaens
- Email: vchristi.christiaens@ugent.be
- Phone: +32 332 40 17
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.