Clinical trial Recruiting at 1 site Observational Ages 18 to 65

Taurine Supplementation for Vascular and Orthostatic Function in Long COVID

Official title: Does Taurine Supplementation Improve Vascular Function and Orthostatic Responses in Long COVID?

Run by York University · NCT07312409 · Data updated 2026-11-12

This study tests whether taking taurine for 12 weeks helps vascular function and upright-balance responses in people with Long COVID.

Quick facts

Study typeObservational
Ages18 Years to 65 Years
SexAll
Enrollment30 (estimated)
SponsorYork University
Academic / other
Locations1 site (Toronto, Ontario)
StatusRecruiting
StartedJune 1, 2026
Main results expectedJune 30, 2027
Study endsDecember 31, 2027
Registry record updatedJune 5, 2026
Trial IDNCT07312409 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults with Long COVID symptoms persisting at least 3 months who can complete a 5-minute tilt test and tolerate self-administered taurine supplementation.

Probably not a fit

Patients not experiencing taurine-related vascular or orthostatic improvements or who cannot complete tilt testing may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines if 12 weeks of self-administered taurine supplementation can improve resting vascular function and the body’s cardiovascular and cerebral responses during head-up tilt in individuals with Long COVID. Researchers will measure resting vascular function with EndoPAT, heart rate variability, and the blood pressure, heart rate, and brain blood flow during a 5-minute tilt test before and after supplementation. The goal is to see whether taurine can enhance vascular health and orthostatic tolerance, potentially reducing related symptoms. Participants are Long COVID patients who have had symptoms for at least 3 months, and the study is led by York University with CIHR collaboration.

Why it matters

Potential benefit: If successful, taurine supplementation could improve vascular function and orthostatic tolerance in Long COVID patients.

How similar studies have gone: Prior evidence suggests taurine can improve blood pressure and vascular function in some populations, supporting exploration in Long COVID.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants will have had symptoms of Long COVID post-infection for at least 3 months

Exclusion Criteria:

* Inability to undergo tilt table testing for 5 minutes
* Inability to transport selves to York University from their homes
* Inability to speak English, or provide a translator
* Blood clotting disorders

Where it's running

  • York University
    Toronto, Ontario, Canada
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.