Tailored weight-management program for overweight Chinese cancer survivors
Lose Little, Live Longer: A Randomised Controlled Feasibility Trial on a Diet-plus-exercise Weight Management Intervention for Overweight Chinese Cancer Survivors
This project will test a culturally tailored weight-management program to help Cantonese- or Mandarin-speaking Chinese cancer survivors who are overweight lose weight, eat better, and become more active.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 102 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | The University of Hong Kong Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Hong Kong) |
| Trial ID | NCT06209996 on ClinicalTrials.gov |
What this trial studies
This feasibility randomized controlled trial will test an adaptive, culturally tailored weight-management intervention (L4) versus an active control in Chinese cancer survivors with overweight or obesity after completion of primary and adjuvant treatment. Participants are Cantonese- or Mandarin-speaking adults (age ≥18) with early-stage (0–II) disease and BMI ≥23 kg/m2 at three-month reassessment, recruited from a face-to-face survivorship clinic. Primary aims are to determine feasibility and acceptability while collecting anthropometric measures (weight, BMI), dietary quality, physical activity, physical and psychosocial functioning, weight-loss self-efficacy, and quality of life. The trial follows CONSORT guidance for feasibility studies and is designed to inform a larger definitive randomized trial rather than to test definitive clinical hypotheses.
Who should consider this trial
Good fit: Ideal candidates are Cantonese- or Mandarin-speaking Chinese adults (≥18) with early-stage (0–II) cancer who have completed primary and adjuvant treatments and have a BMI ≥23 kg/m2 at a three-month reassessment while attending the survivorship clinic.
Not a fit: Patients with advanced or metastatic disease, non-Chinese patients, or those with significant communication difficulties, mobility impairments, or cognitive disabilities are unlikely to be eligible or to benefit from this intervention.
Why it matters
Potential benefit: If successful, the program could help survivors lose weight, increase physical activity, and improve quality of life while providing a model for larger survivorship services.
How similar studies have performed: Lifestyle and weight-loss programs for cancer survivors have produced modest weight loss and quality-of-life gains in prior studies, but adaptive interventions specifically tailored to Cantonese- or Mandarin-speaking Chinese survivors remain relatively untested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Chinese cancer survivors attending the one-off face-to-face survivorship care clinic * who are Cantonese- or Mandarin- speaking * aged 18 or above * diagnosed with early-stage disease (stage 0-II) * have completed primary and adjuvant treatments such as chemotherapy and radiotherapy * and with a BMI ≥ 23 kg/m2, as indicative as overweight or obesity using Asia-Pacific BMI cutoffs at 3-months reassessment Exclusion Criteria: * Non-Chinese survivors with advanced or metastatic disease * who have communication difficulties, mobility impairment or cognitive disabilities
Where this trial is running
Hong Kong
- The University of Hong Kong Jockey Club Institute of Cancer Care — Hong Kong, Hong Kong (Recruiting)
Study contacts
- Principal investigator: Danielle Ng, PhD — School of Public Health, The University of Hong Kong
- Study coordinator: Danielle Ng, PhD
- Email: dwlng@hku.hk
- Phone: +852 39179897
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.