Willem AI for early detection of aortic stenosis from a 12‑lead ECG

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a multicenter observational study using both retrospective and prospective ECG data to validate the Willem AI algorithm's ability to distinguish aortic stenosis from non‑AS patients. De‑identified digital 12‑lead ECG recordings of at least 10 seconds will be paired with clinical data and a transthoracic echocardiogram performed within ±90 days to establish ground truth. The algorithm's ECG-based classifications will be compared to echocardiographic diagnoses across participating centers in Germany. No exclusion criteria are defined beyond the required ECG and echocardiogram availability.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years;
* All available 12-lead ECG with a 10 seconds minimum length on raw data digital format will be included
* Available clinical data corresponding to each ECG to confirm patient demographics and Aortic Stenosis diagnosis
* Available transthoracic echocardiogram (TTE) within +/- 90 days of each ECG recording

No exclusion criteria are defined for this study.

Where it's running

• Universitätsklinikum Bonn
  Bonn, Germany Recruiting
• Technical University of Munich
  Munich, Germany Recruiting

Study contacts

• Study coordinator: Manuel Marina-Breysse, MD, PhD
• Email: clinical@idoven.ai
• Phone: +34669752391

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.