Clinical trial Recruiting at 1 site Phase 3 Interventional Ages 18 to 80

Surgery for solid-dominant lung cancer

Official title: Segmentectomy for Solid-dominant GGO-featured Invasive Lung Cancer With Size of 2-3cm: a Single-arm, Multi-center, Phase III Trial

Run by Fudan University · NCT06634966 · Data updated 2026-11-12

This study is testing if a specific lung surgery called segmentectomy can help people with a certain type of lung cancer live longer and breathe better after the operation.

Quick facts

PhasePhase 3
Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment277 (estimated)
SponsorFudan University
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Shanghai, Shanghai Municipality)
StatusRecruiting
StartedJuly 1, 2024
Main results expectedDecember 31, 2026
Study endsJune 30, 2027
Registry record updatedOctober 10, 2024
Trial IDNCT06634966 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 to 80 with solid-dominant invasive lung adenocarcinoma sized between 2-3 cm who have not undergone prior lung cancer surgery.

Probably not a fit

Patients with tumors that cannot be completely resected or those who have received prior lung cancer treatments may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of segmentectomy, a surgical procedure, for patients with solid-dominant invasive lung adenocarcinoma measuring 2-3 cm. The study will assess the 5-year disease-free survival rates and post-operative lung function of participants. Eligible patients will undergo segmentectomy and will be monitored for their recovery and outcomes over time.

Why it matters

Potential benefit: If successful, this study could improve surgical treatment options and outcomes for patients with specific types of lung cancer.

How similar studies have gone: Other studies have shown promising results with segmentectomy for lung cancer, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients who sign the informed consent form and are willing to complete the study according to the plan;
* Aged from 18 to 80 years old;
* ECOG equals 0 or 1;
* Not receiving lung cancer surgery before;
* Confirmed to be invasive lung adenocarcinoma intraoperatively or postoperatively;
* Ground glass-dominant lung nodules
* Consolidation-to-tumor ratio (CTR) ranges from 0.5 to 1, and tumor size ranges from 2 to 3cm;
* cN0 without distant metastasis;
* Tumors could be completely resected assed by surgeons;
* Not receiving chemotherapy or radiotherapy before.

Exclusion Criteria:

* CTR is not 0.5-1, or size is not 2-3cm;
* Tumors could not be completely resected assed by surgeons;
* Not lung adenocarcinoma diagnosed cytologically or pathologically;
* Receiving lung cancer surgery before;
* Receiving radiotherapy or chemotherapy.

Where it's running

  • Fudan University Shanghai Cancer Center
    Shanghai, Shanghai Municipality, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.