Surgery for early-stage lung cancer with ground glass nodules

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of segmentectomy, a lung-sparing surgical procedure, for patients with ground glass-dominant invasive lung adenocarcinoma measuring 2-3 cm. The study will assess the 5-year disease-free survival rates and post-operative lung function of participants. Eligible patients will undergo segmentectomy and will be monitored for their recovery and long-term outcomes. The trial is part of the Eastern Cooperative Thoracic Oncology Project (ECTOP) and focuses on a specific subset of lung cancer patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients who sign the informed consent form and are willing to complete the study according to the plan;
* Aged from 18 to 80 years old;
* ECOG equals 0 or 1;
* Not receiving lung cancer surgery before;
* Confirmed to be invasive lung adenocarcinoma intraoperatively or postoperatively;
* Ground glass-dominant lung nodules
* Consolidation-to-tumor ratio (CTR) ranges from 0 to 0.5, and tumor size ranges from 2 to 3cm;
* cN0 without distant metastasis;
* Tumors could be completely resected assed by surgeons;
* Not receiving chemotherapy or radiotherapy before.

Exclusion Criteria:

* CTR is not 0-0.5, or size is not 2-3cm;
* Tumors could not be completely resected assed by surgeons;
* Not lung adenocarcinoma diagnosed cytologically or pathologically;
* Receiving lung cancer surgery before;
* Receiving radiotherapy or chemotherapy.

Where it's running

• Fudan University Shanghai Cancer Center
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Principal investigator: Haiquan Chen, M.D. — Fudan University
• Study coordinator: Fangqiu Fu, M.D.
• Email: fufangqiu12@163.com
• Phone: +86-13122677592

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.